INT84831

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Context Info
Confidence 0.02
First Reported 1999
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.53
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA processing (Rbm39) RNA binding (Rbm39) nucleus (Rbm39)
Anatomy Link Frequency
pyramidal neurons 2
cerebellum 2
Rbm39 (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 7 97.88 Very High Very High Very High
central sensitization 9 84.44 Quite High
Visceral pain 1 70.24 Quite High
IPN 9 69.60 Quite High
Spinal cord 10 65.92 Quite High
Neuropathic pain 4 61.24 Quite High
Glutamate receptor 13 50.00 Quite Low
anesthesia 2 50.00 Quite Low
Inflammation 9 29.92 Quite Low
Hyperalgesia 4 28.88 Quite Low
Disease Link Frequency Relevance Heat
Nociception 26 88.08 High High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

1 70.24 Quite High
Inflammatory Pain 9 69.60 Quite High
Injury 2 67.28 Quite High
Neuropathic Pain 4 61.24 Quite High
Hyperalgesia 5 60.04 Quite High
Targeted Disruption 1 48.64 Quite Low
INFLAMMATION 9 29.92 Quite Low
Pain 8 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, patch-clamp recordings of acutely dissociated CA1 hippocampal pyramidal neurons from (-/-) and (+/+) mice were undertaken to investigate the effects of barbiturates on kainate-activated AMPA receptors and GABA-activated GABA(A) receptors.
Spec (investigate) Regulation (effects) of Spec (investigate) Positive_regulation (kainate-activated) of receptors in pyramidal neurons
1) Confidence 0.02 Published 1999 Journal Anesthesiology Section Body Doc Link 10551584 Disease Relevance 0 Pain Relevance 0
The rapid alterations in the composition of synaptic AMPA receptors induced by various stimuli may occur in the cerebellum, the hippocampus and the cortex.
Regulation (alterations) of Positive_regulation (induced) of receptors in cerebellum associated with hippocampus
2) Confidence 0.00 Published 2010 Journal Mol Pain Section Body Doc Link PMC2823608 Disease Relevance 0.46 Pain Relevance 0.47

General Comments

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