INT84886

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Context Info
Confidence 0.51
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 3
Disease Relevance 1.57
Pain Relevance 1.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (APC, PPARD) cell differentiation (PPARD) nucleoplasm (PPARD)
DNA binding (PPARD) protein complex assembly (APC) lipid metabolic process (PPARD)
APC (Homo sapiens)
PPARD (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 15 99.84 Very High Very High Very High
Disease Link Frequency Relevance Heat
INFLAMMATION 6 99.12 Very High Very High Very High
Colon Cancer 9 94.12 High High
Repression 3 89.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs.
APC Regulation (regulated) of PPARdelta associated with inflammation and cinod
1) Confidence 0.51 Published 1999 Journal Cell Section Title Doc Link 10555149 Disease Relevance 0.55 Pain Relevance 0.41
These findings suggest that NSAIDs inhibit tumorigenesis through inhibition of PPARdelta, the gene for which is normally regulated by APC.
APC Regulation (regulated) of PPARdelta associated with cinod
2) Confidence 0.37 Published 1999 Journal Cell Section Abstract Doc Link 10555149 Disease Relevance 0.47 Pain Relevance 0.44
PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs.
APC Regulation (target) of PPARdelta associated with inflammation and cinod
3) Confidence 0.22 Published 1999 Journal Cell Section Title Doc Link 10555149 Disease Relevance 0.55 Pain Relevance 0.41

General Comments

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