INT84911

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.11
First Reported 1999
Last Reported 2010
Negated 5
Speculated 0
Reported most in Body
Documents 43
Total Number 43
Disease Relevance 19.85
Pain Relevance 4.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SUGT1) mitosis (SUGT1)
Anatomy Link Frequency
plasma 2
T cell 2
Shoulders 1
blood 1
artery 1
SUGT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Catechol-O-methyltransferase 203 100.00 Very High Very High Very High
alcohol 220 99.00 Very High Very High Very High
spinal inflammation 21 98.62 Very High Very High Very High
Arthritis 234 96.72 Very High Very High Very High
Inflammation 53 96.12 Very High Very High Very High
rheumatoid arthritis 26 94.76 High High
Migraine 8 91.32 High High
dopamine receptor 8 89.52 High High
Dopamine 85 88.04 High High
cytokine 31 87.72 High High
Disease Link Frequency Relevance Heat
Anxiety Disorder 107 99.90 Very High Very High Very High
Cancer 354 99.80 Very High Very High Very High
Infection 65 99.78 Very High Very High Very High
Disease 275 99.08 Very High Very High Very High
Seronegative Spondarthritis 140 99.08 Very High Very High Very High
Frailty 3 99.06 Very High Very High Very High
Aging 27 98.92 Very High Very High Very High
Breast Cancer 35 98.78 Very High Very High Very High
Stomach Cancer 9 98.76 Very High Very High Very High
Obesity 269 98.68 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Meanwhile, Kim et al.59 reported that the allele frequency of the Asp40 allele was 39.7% in the Korean alcohol dependent group, which is consistent with previous studies demonstrating a higher Asp40 allele frequency in the Asian population.
Gene_expression (frequency) of allele associated with alcohol
1) Confidence 0.11 Published 2006 Journal Yonsei Medical Journal Section Body Doc Link PMC2687624 Disease Relevance 0.36 Pain Relevance 0.26
Meanwhile, Kim et al.59 reported that the allele frequency of the Asp40 allele was 39.7% in the Korean alcohol dependent group, which is consistent with previous studies demonstrating a higher Asp40 allele frequency in the Asian population.
Gene_expression (frequency) of Asp40 allele associated with alcohol
2) Confidence 0.11 Published 2006 Journal Yonsei Medical Journal Section Body Doc Link PMC2687624 Disease Relevance 0.36 Pain Relevance 0.27
In comparison, two Japanese population studies show that Ala12 allele carriers have significantly lower plasma levels of adiponectin than Pro12 allele carriers [187, 188] and another two case-control studies in either diabetic patients or women with PCOS fail to find significant change in serum adiponectin levels [189, 190].
Gene_expression (levels) of allele in plasma associated with diabetes mellitus and polycystic ovary syndrome
3) Confidence 0.07 Published 2009 Journal PPAR Research Section Body Doc Link PMC2669649 Disease Relevance 0.93 Pain Relevance 0.07
is probably related to gastric mucosa atrophy and Helipobacteria pylori infection since the presence of Ala12 allele does not increase the risk of gastric cancer in H. pylori-negative subjects [199].
Gene_expression (presence) of allele associated with frailty, stomach cancer and infection
4) Confidence 0.07 Published 2009 Journal PPAR Research Section Body Doc Link PMC2669649 Disease Relevance 1.43 Pain Relevance 0.09
Risk reduction is higher in Asians carrying Ala12 allele (35%) than in Northern Americans and Europeans with the Ala12 genotype (18% and 15%, resp.) compared to their own Pro12 allele controls.
Gene_expression (controls) of allele
5) Confidence 0.07 Published 2009 Journal PPAR Research Section Body Doc Link PMC2669649 Disease Relevance 0.78 Pain Relevance 0
The A (Met) allele was detected with the primers 5'-CGGGTCAGGCATGCACACCTTGTCCTTCCT-3' and 5'-TGCTGTCACCAGGGGCGAGGCTCATCA-3', generating a 116 bp product.
Gene_expression (detected) of allele
6) Confidence 0.06 Published 2007 Journal Behav Brain Funct Section Body Doc Link PMC1779796 Disease Relevance 0.42 Pain Relevance 0.19
Consistent with Reuter et al. [1] the gene loci were considered in two ways: (1) presence of an allele (DRD2 TaqI A1 or COMT Val) and (2) genotype.
Gene_expression (presence) of allele associated with catechol-o-methyltransferase
7) Confidence 0.05 Published 2007 Journal Behav Brain Funct Section Body Doc Link PMC1779796 Disease Relevance 0.11 Pain Relevance 0.08
Men possessing the COMT Met allele had lower BIS scores than men without this allele, whilst the inverse pattern occurred amongst women [1].
Gene_expression (possessing) of allele associated with catechol-o-methyltransferase
8) Confidence 0.05 Published 2007 Journal Behav Brain Funct Section Body Doc Link PMC1779796 Disease Relevance 0 Pain Relevance 0.34
The COMT Met and Val allele frequencies were .46 and .54, respectively.
Gene_expression (frequencies) of allele associated with catechol-o-methyltransferase
9) Confidence 0.05 Published 2007 Journal Behav Brain Funct Section Body Doc Link PMC1779796 Disease Relevance 0 Pain Relevance 0.13
Enoch et al. [9] found that females homozygous for the COMT Met allele reported the highest HA scores.
Gene_expression (homozygous) of allele associated with catechol-o-methyltransferase
10) Confidence 0.05 Published 2007 Journal Behav Brain Funct Section Body Doc Link PMC1779796 Disease Relevance 0 Pain Relevance 0.26
The G (Val) allele was detected using the primers 5'-TCACCCAGCGGATGGTGGATTTCGCTGGGG-3' and 5'-AACGTGGTGTGAACACCTGGTGGGGAG-3', yielding a 143 bp product.
Gene_expression (detected) of allele
11) Confidence 0.05 Published 2007 Journal Behav Brain Funct Section Body Doc Link PMC1779796 Disease Relevance 0.46 Pain Relevance 0.20
Effect sizes for the presence of each allele in relation to HA and NS scores, in both samples, were calculated.
Gene_expression (presence) of allele
12) Confidence 0.05 Published 2007 Journal Behav Brain Funct Section Body Doc Link PMC1779796 Disease Relevance 0 Pain Relevance 0.04
Genotype data were reported in a comma-delimited flat-file format that contained the SNP and sample identifiers for each allele detected.
Gene_expression (detected) of allele
13) Confidence 0.04 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2288787 Disease Relevance 0 Pain Relevance 0
We found a statistically significant difference in allele (p = 0.018; OR = 1.46 95 % CI: 1.066 to 2.023) and genotype (trend chi2 = 5.46, df = 1, p = 0.019) frequencies of TNF-beta gene, between cases and controls.
Gene_expression (frequencies) of allele
14) Confidence 0.03 Published 2009 Journal J. Neurol. Section Abstract Doc Link 19253056 Disease Relevance 0.94 Pain Relevance 0.63
The presence of the TNF2 allele has also been linked to increased susceptibility to and severity in a variety of autoimmune and inflammatory disorders, including RA, systemic lupus erythematosus, and ankylosing spondylitis.
Gene_expression (presence) of allele associated with spinal inflammation, inflammation, rheumatoid arthritis and systemic lupus erythematosus
15) Confidence 0.02 Published 2006 Journal Immunobiology Section Abstract Doc Link 16446172 Disease Relevance 1.27 Pain Relevance 0.44
Dallinga-Thie et al [22,23] and Shoulders et al [24,25] reported an association between levels of apoCIII and S2 allele.
Gene_expression (levels) of allele in Shoulders
16) Confidence 0.02 Published 2002 Journal BMC Genet Section Body Doc Link PMC116591 Disease Relevance 0.39 Pain Relevance 0
To further evaluate the impact of the rs5275 SNP on the risk of developing breast cancer, the haplotypes were separated into groups according to the presence of the rs5275 T or C allele.
Gene_expression (presence) of allele associated with breast cancer
17) Confidence 0.02 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2992523 Disease Relevance 0.40 Pain Relevance 0
Where p' is the is the frequency of the A allele in the second (offspring) generation, p is its frequency in the first (parental) generation and q is the frequency in the first generation of the S allele.
Gene_expression (generation) of allele
18) Confidence 0.02 Published 2010 Journal BMC Med Genet Section Body Doc Link PMC2829010 Disease Relevance 0.43 Pain Relevance 0
Thus, the 825T allele of the beta3 subunit of heterotrimeric G proteins, associated with enhanced PTX-sensitive G protein signaling, was expected to determine the alpha(2)-adrenoceptor-, but not the alpha(1)-adrenoceptor-, mediated reduction in coronary blood flow (CBF).
Gene_expression (expected) of allele in blood
19) Confidence 0.02 Published 1999 Journal Circ. Res. Section Abstract Doc Link 10559144 Disease Relevance 0.45 Pain Relevance 0.16
The A24-LCL, a human B-lymphoblastoid cell line (B-LCL) which expresses the HLA-A24 allele, was pulsed with peptides and used for a stimulator or target in cytotoxicity assay.
Gene_expression (expresses) of allele in A24
20) Confidence 0.02 Published 2010 Journal J Transl Med Section Body Doc Link PMC2949666 Disease Relevance 0.22 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox