INT84925

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.65
First Reported 1999
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 11
Total Number 13
Disease Relevance 4.13
Pain Relevance 3.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (NGF) signal transduction (NGF) extracellular space (NGF)
extracellular region (NGF)
Anatomy Link Frequency
nerve 3
corpus 1
pancreas 1
annulus 1
1321N1 1
NGF (Homo sapiens)
Pain Link Frequency Relevance Heat
Nerve growth factor 57 100.00 Very High Very High Very High
agonist 4 99.96 Very High Very High Very High
Trk A 2 97.76 Very High Very High Very High
Nicotine 2 97.72 Very High Very High Very High
vaginimus 2 91.12 High High
Pain 34 89.64 High High
gABA 2 89.12 High High
Inflammation 36 87.84 High High
nociceptor 6 81.36 Quite High
backache 3 81.28 Quite High
Disease Link Frequency Relevance Heat
Anaplastic Astrocytoma 2 99.28 Very High Very High Very High
Pancreatic Cancer 10 98.28 Very High Very High Very High
Breast Cancer 1 94.04 High High
Dyspareunia 2 91.12 High High
Bladder Disease 2 90.32 High High
Pain 33 88.96 High High
INFLAMMATION 40 87.84 High High
Nociception 30 86.04 High High
Cancer 10 82.16 Quite High
Low Back Pain 3 81.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We investigated the expression of NGF receptors (NGFRs: TrkA and p75NGFR) mRNA in 56 human primary pancreatic cancers, using real-time quantitative reverse transcription-PCR.
Spec (investigated) Transcription (expression) of NGF associated with nerve growth factor and pancreatic cancer
1) Confidence 0.65 Published 2005 Journal Oncol. Rep. Section Abstract Doc Link 15944784 Disease Relevance 0.89 Pain Relevance 0.33
RESULTS: Northern blot analysis indicated that NGF and TrkA mRNA levels were increased 2.7-fold and 5.6-fold, respectively (P <.05 and P <.05), in pancreatic cancer tissues compared with the normal pancreas tissue.
Transcription (levels) of NGF in pancreas
2) Confidence 0.53 Published 1999 Journal J. Clin. Oncol. Section Body Doc Link 10561305 Disease Relevance 0.17 Pain Relevance 0
MATERIALS AND METHODS: The mRNA levels of pain-related neurotrophic factors, NGF, GDNF and IL-6, were examined in the sural nerves of 22 painful and non-painful patients with acute necrotizing vasculitic neuropathies, together with their concomitant soluble receptors (p75, GFR(alpha)-1 and IL-6R(alpha)).
Transcription (levels) of NGF in nerves
3) Confidence 0.51 Published 2003 Journal Intern. Med. Section Body Doc Link 14686749 Disease Relevance 0 Pain Relevance 0
NGF mRNA expression was more closely correlated with that of p75 in painful neuropathy with relatively preserved large fiber density, compared with non-painful neuropathy, though the NGF mRNA level in painful neuropathy was lower than that in non-painful neuropathy.
Transcription (level) of NGF
4) Confidence 0.51 Published 2003 Journal Intern. Med. Section Body Doc Link 14686749 Disease Relevance 0 Pain Relevance 0
NGF mRNA expression was more closely correlated with that of p75 in painful neuropathy with relatively preserved large fiber density, compared with non-painful neuropathy, though the NGF mRNA level in painful neuropathy was lower than that in non-painful neuropathy.
Transcription (expression) of NGF
5) Confidence 0.51 Published 2003 Journal Intern. Med. Section Body Doc Link 14686749 Disease Relevance 0 Pain Relevance 0
Gigante and colleagues recently reported the presence of NGF mRNA and the high-affinity tyrosine kinase A receptor and the low-affinity p75 receptor in the rounded cells in the disc annulus and nucleus pulposus [5].
Transcription (presence) of NGF in nucleus pulposus associated with nerve growth factor
6) Confidence 0.43 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2575628 Disease Relevance 0.38 Pain Relevance 0.35
We have, in an earlier study, demonstrated the occurrence of the NGF receptor p75 in human corpus and cervix uteri in pregnancy and labor [36] and have unpublished data showing mRNA expression for NGF?
Transcription (expression) of NGF in cervix associated with nerve growth factor
7) Confidence 0.42 Published 2008 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2254422 Disease Relevance 0.72 Pain Relevance 1.03
-secretase inhibitors; glycogen synthase kinase inhibitors; growth hormone releasing hormone; huperzine A; Hydergine™; ispronicline; lecozotan; lethicin; lithium carbonate; melatonin; milacemide; neramexane; muscarinic receptor agonists; nerve growth factor (NGF) gene therapy and mimics; nicergoline; nicotinic receptor modulators; nicotine; nimodipine; paclitaxel; peroxisome proliferator-activated receptor (PPAR)-?
Transcription (therapy) of nerve growth factor in nerve associated with nerve growth factor, nicotine and agonist
8) Confidence 0.17 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2656293 Disease Relevance 0.34 Pain Relevance 0.28
-secretase inhibitors; glycogen synthase kinase inhibitors; growth hormone releasing hormone; huperzine A; Hydergine™; ispronicline; lecozotan; lethicin; lithium carbonate; melatonin; milacemide; neramexane; muscarinic receptor agonists; nerve growth factor (NGF) gene therapy and mimics; nicergoline; nicotinic receptor modulators; nicotine; nimodipine; paclitaxel; peroxisome proliferator-activated receptor (PPAR)-?
Transcription (therapy) of NGF in nerve associated with nerve growth factor, nicotine and agonist
9) Confidence 0.17 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2656293 Disease Relevance 0.34 Pain Relevance 0.28
Gigante and colleagues recently reported the presence of NGF mRNA and the high-affinity tyrosine kinase A receptor and the low-affinity p75 receptor in the rounded cells in the disc annulus and nucleus pulposus [5].
Transcription (presence) of NGF in annulus associated with nerve growth factor
10) Confidence 0.15 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2575628 Disease Relevance 0.38 Pain Relevance 0.35
We have, in an earlier study, demonstrated the occurrence of the NGF receptor p75 in human corpus and cervix uteri in pregnancy and labor [36] and have unpublished data showing mRNA expression for NGF?
Transcription (expression) of NGF in corpus associated with nerve growth factor
11) Confidence 0.14 Published 2008 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2254422 Disease Relevance 0.72 Pain Relevance 1.03
Effects of lannotinidines A–F on neurotrophic factor biosynthesis in 1321N1 human astrocytoma cells were examined by determining NGF mRNA expression. 1321N1 cells were incubated with 30 ?
Transcription (expression) of NGF in 1321N1 associated with anaplastic astrocytoma
12) Confidence 0.12 Published 2008 Journal The Open Medicinal Chemistry Journal Section Body Doc Link PMC2709475 Disease Relevance 0.10 Pain Relevance 0
Two lannotinidines F (3) and E (4) contain cyclobutane ring elevated NGF mRNA expression.
Transcription (expression) of NGF
13) Confidence 0.12 Published 2008 Journal The Open Medicinal Chemistry Journal Section Body Doc Link PMC2709475 Disease Relevance 0.09 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox