INT84945

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Context Info
Confidence 0.61
First Reported 1999
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 1.80
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (BMP2) growth (BMP2) extracellular region (BMP2)
embryo development (BMP2) protein complex (BMP2) cell-cell signaling (BMP2)
BMP2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Trigeminal neuralgia 2 96.24 Very High Very High Very High
Osteoarthritis 6 82.08 Quite High
fifth nerve 2 75.00 Quite High
metalloproteinase 8 70.00 Quite High
acular 3 50.00 Quite Low
cINOD 2 50.00 Quite Low
cytokine 10 21.76 Low Low
Facet joint 38 5.00 Very Low Very Low Very Low
imagery 28 5.00 Very Low Very Low Very Low
antagonist 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nerve Sheath Neoplasms 2 99.56 Very High Very High Very High
Neurilemmoma 3 98.88 Very High Very High Very High
Malignant Neoplastic Disease 2 97.84 Very High Very High Very High
Headache 2 96.24 Very High Very High Very High
Heterotopic Ossification 30 95.08 Very High Very High Very High
Neurodegenerative Disease 1 94.16 High High
Osteoporosis 16 83.44 Quite High
Osteoarthritis 18 82.08 Quite High
Disease 22 80.88 Quite High
Intervertebral Disk Degeneration 68 77.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Rabbits were divided into three groups: 1) control (saline in pump); 2) nonsteroidal anti-inflammatory drug (ketorolac in pump); 3) nonsteroidal anti-inflammatory drug (ketorolac in pump) and bone morphogenetic protein (bone graft soaked in a 3.0 mg solution of recombinant human bone morphogenetic protein-2.
Transcription (solution) of bone morphogenetic protein-2
1) Confidence 0.61 Published 1999 Journal Spine Section Body Doc Link 10562982 Disease Relevance 0 Pain Relevance 0
The mRNA transcriptions of BMP 2, 3, 4 and 5 in 12 cases of schwannoma, four cases of malignant schwannoma and three cases of trigeminal neuralgia were detected using an in situ hybridization technique.
Transcription (transcriptions) of BMP 2 associated with malignant neoplastic disease, neurilemmoma and trigeminal neuralgia
2) Confidence 0.52 Published 2001 Journal Kaohsiung J. Med. Sci. Section Abstract Doc Link 11411255 Disease Relevance 0.79 Pain Relevance 0.25
G transition at nucleotide 116 in exon 2 of BMP-2, resulting in a Ser?
Transcription (transition) of BMP-2
3) Confidence 0.51 Published 2008 Journal Eur Spine J Section Body Doc Link PMC2443260 Disease Relevance 0.68 Pain Relevance 0.04
In addition, immunohistochemical studies demonstrated that BMP-2 and TGF-?
Transcription (demonstrated) of BMP-2
4) Confidence 0.51 Published 2008 Journal Eur Spine J Section Body Doc Link PMC2443260 Disease Relevance 0.18 Pain Relevance 0
In addition, the in vivo injection of AdLMP-1 resulted in a significant elevation of mRNA levels of LMP-1, BMP-2, and BMP-7.
Transcription (levels) of BMP-2
5) Confidence 0.45 Published 2006 Journal J Orthop Sci Section Body Doc Link PMC2778630 Disease Relevance 0.07 Pain Relevance 0.03
The mRNA levels of BMP-2 and BMP-7 were also upregulated.
Transcription (levels) of BMP-2
6) Confidence 0.45 Published 2006 Journal J Orthop Sci Section Body Doc Link PMC2778630 Disease Relevance 0.08 Pain Relevance 0.04

General Comments

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