INT85056

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Context Info
Confidence 0.42
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.96
Pain Relevance 1.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (SCN11A) transmembrane transport (SCN11A)
Anatomy Link Frequency
neurons 2
SCN11A (Homo sapiens)
Pain Link Frequency Relevance Heat
sodium channel 7 100.00 Very High Very High Very High
dorsal root ganglion 6 97.72 Very High Very High Very High
Eae 4 96.80 Very High Very High Very High
Neuropathic pain 2 96.60 Very High Very High Very High
tetrodotoxin 2 83.96 Quite High
Hyperalgesia 1 76.88 Quite High
Sciatic nerve 1 68.00 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 6 97.72 Very High Very High Very High
Injury 4 96.80 Very High Very High Very High
Neuropathic Pain 2 96.60 Very High Very High Very High
Hyperalgesia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Transcripts of NaN and SNS, two sensory neuron-specific TTX-R sodium channels, are significantly down-regulated as is the TTX-R sodium current, while transcripts of the TTX-S alpha-III sodium channel and a rapidly repriming TTX-S Na current are up-regulated in small diameter DRG neurons.
Negative_regulation (down-regulated) of Transcription (Transcripts) of NaN in neurons associated with dorsal root ganglion and sodium channel
1) Confidence 0.42 Published 1999 Journal Pain Section Abstract Doc Link 10568868 Disease Relevance 0.96 Pain Relevance 1.18

General Comments

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