INT85182

Context Info Confidence 0.68 First Reported 1999 Last Reported 2008 Negated 0 Speculated 2 Reported most in Abstract Documents 5 Total Number 8 Disease Relevance 1.27 Pain Relevance 0.83

plasma membrane (Oxtr) response to stress (Oxtr) signal transducer activity (Oxtr)

Anatomy Link Frequency uterus 2 neurons 1 uterine 1 Oxtr (Rattus norvegicus)

Pain Link Frequency Relevance Heat Dynorphin 4 99.78 Enkephalin 2 99.20 projection neuron 1 87.60 Spinal cord 7 86.80 anesthesia 2 80.40 Dismenorea 11 78.32 Neuropeptide 3 75.00 Acupuncture 6 50.00

Disease Link Frequency Relevance Heat Vibrio Infection 1 90.88 Shock 4 89.16 Reprotox - General 1 2 82.92 Nicotine Addiction 6 82.04 Dysmenorrhea 3 78.32 Premature Birth 4 75.32

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

RT-PCR method was used to observe the oxytocin receptor (OTR) and vasopressin receptor (VPR) mRNA expressions in the uterus in each group.

Transcription (expressions) of OTR in uterus

1) Confidence 0.68 Published 2008 Journal Zhongguo Zhen Jiu Section Body Doc Link 18972735 Disease Relevance 0.08 Pain Relevance 0

RT-PCR method was used to observe the oxytocin receptor (OTR) and vasopressin receptor (VPR) mRNA expressions in the uterus in each group.

Transcription (expressions) of oxytocin receptor in uterus

2) Confidence 0.68 Published 2008 Journal Zhongguo Zhen Jiu Section Body Doc Link 18972735 Disease Relevance 0.08 Pain Relevance 0

Furthermore, the expression levels of oxytocin receptor (OTR) mRNA in the myometrial strips were investigated by real-time PCR.

Spec (investigated) Transcription (levels) of oxytocin receptor

3) Confidence 0.53 Published 2006 Journal Reproduction Section Abstract Doc Link 16885542 Disease Relevance 0.39 Pain Relevance 0.08

Furthermore, the expression levels of oxytocin receptor (OTR) mRNA in the myometrial strips were investigated by real-time PCR.

Spec (investigated) Transcription (levels) of OTR

4) Confidence 0.53 Published 2006 Journal Reproduction Section Abstract Doc Link 16885542 Disease Relevance 0.39 Pain Relevance 0.08

Of the spinally projecting neurons in the PVH, approximately 40% expressed dynorphin mRNA, 40% expressed oxytocin mRNA, and 20% expressed enkephalin mRNA.

Transcription (expressed) of oxytocin mRNA in neurons associated with dynorphin and enkephalin

5) Confidence 0.39 Published 2001 Journal J. Comp. Neurol. Section Abstract Doc Link 11283961 Disease Relevance 0.09 Pain Relevance 0.59

We also examined the regulatory effects of estrogen and progesterone on OTR mRNA expression in ovariectomized nonpregnant sheep.

Transcription (expression) of OTR

6) Confidence 0.24 Published 1999 Journal Endocrinology Section Abstract Doc Link 10579336 Disease Relevance 0.16 Pain Relevance 0.08

Progesterone significantly inhibited myometrial OTR mRNA expression in nonpregnant sheep and estradiol antagonized progesterone's inhibitory effect.

Transcription (expression) of OTR

7) Confidence 0.24 Published 1999 Journal Endocrinology Section Abstract Doc Link 10579336 Disease Relevance 0.07 Pain Relevance 0

Fundal OTR mRNA rose significantly compared with the lower uterine segment during spontaneous labor.

Transcription (rose) of OTR in uterine

8) Confidence 0.22 Published 2001 Journal J. Endocrinol. Section Abstract Doc Link 11739010 Disease Relevance 0 Pain Relevance 0

General Comments

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