INT85184

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Context Info
Confidence 0.26
First Reported 1999
Last Reported 2003
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.19
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Oxtr) response to stress (Oxtr) signal transducer activity (Oxtr)
Anatomy Link Frequency
uterine smooth muscle 2
Oxtr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dismenorea 1 66.08 Quite High
anesthesia 1 38.72 Quite Low
Disease Link Frequency Relevance Heat
Smooth Muscle Tumor 3 97.96 Very High Very High Very High
Endometrial Stromal Sarcoma 7 96.96 Very High Very High Very High
Cancer 3 94.96 High High
Uterine Fibroids 9 77.28 Quite High
Shock 2 75.00 Quite High
Leiomyosarcoma 5 72.32 Quite High
Dysmenorrhea 1 66.08 Quite High
Metaplasia 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present study aimed to investigate oxytocin receptor (OTR) expression in the normal uterus, and particularly in uterine smooth muscle tumors and endometrial stromal sarcomas (ESSs) because these tumors can be difficult to distinguish.
Spec (investigate) Negative_regulation (investigate) of Spec (investigate) Gene_expression (expression) of OTR in uterine smooth muscle associated with endometrial stromal sarcoma, smooth muscle tumor and cancer
1) Confidence 0.26 Published 2003 Journal Am. J. Surg. Pathol. Section Abstract Doc Link 14576480 Disease Relevance 1.12 Pain Relevance 0.07
Progesterone significantly inhibited myometrial OTR mRNA expression in nonpregnant sheep and estradiol antagonized progesterone's inhibitory effect.
Negative_regulation (inhibited) of Gene_expression (expression) of OTR
2) Confidence 0.19 Published 1999 Journal Endocrinology Section Abstract Doc Link 10579336 Disease Relevance 0.07 Pain Relevance 0

General Comments

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