INT85191

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.67
First Reported 1999
Last Reported 2006
Negated 1
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 0.94
Pain Relevance 1.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (FOSL1) nucleus (FOSL1)
Anatomy Link Frequency
neurons 4
MBH 2
medial 2
TMJ 2
FOSL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 8 99.68 Very High Very High Very High
bradykinin 3 99.44 Very High Very High Very High
Snapping jaw 6 98.40 Very High Very High Very High
Opioid 4 97.48 Very High Very High Very High
Endogenous opioid 4 87.92 High High
Inflammation 1 75.36 Quite High
anesthesia 1 63.80 Quite High
Pain 1 54.40 Quite High
medulla 1 51.12 Quite High
Disease Link Frequency Relevance Heat
Death 4 99.76 Very High Very High Very High
Temporomandibular Joint Syndrome 6 98.40 Very High Very High Very High
INFLAMMATION 1 75.36 Quite High
Pain 1 54.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Active integrin antagonist did not affect Fos-LI produced after injection of bradykinin alone into the TMJ.
Positive_regulation (after) of Gene_expression (produced) of Fos-LI in TMJ associated with snapping jaw, antagonist and bradykinin
1) Confidence 0.67 Published 2006 Journal Pain Section Abstract Doc Link 16762506 Disease Relevance 0.56 Pain Relevance 0.93
Fos/FRA expression was not increased in GnRH neurons found in any other area.
Neg (not) Positive_regulation (increased) of Gene_expression (expression) of FRA in neurons
2) Confidence 0.01 Published 1999 Journal Endocrinology Section Abstract Doc Link 10579360 Disease Relevance 0.10 Pain Relevance 0.20
Again, this increase in Fos/FRA expression in GnRH neurons was limited to the MBH.
Positive_regulation (increase) of Gene_expression (expression) of FRA in neurons
3) Confidence 0.01 Published 1999 Journal Endocrinology Section Abstract Doc Link 10579360 Disease Relevance 0.09 Pain Relevance 0.21
These five ewes had a 6-fold increase in the percentage of GnRH neurons in the medial basal hypothalamus (MBH) expressing Fos/FRA, compared with control ewes that had no LH pulses before death.
Positive_regulation (increase) of Gene_expression (expressing) of FRA in medial associated with death
4) Confidence 0.01 Published 1999 Journal Endocrinology Section Abstract Doc Link 10579360 Disease Relevance 0.10 Pain Relevance 0.20
This treatment increased Fos/FRA expression in MBH GnRH neurons approximately 10-fold compared with control rams.
Positive_regulation (increased) of Gene_expression (expression) of FRA in MBH
5) Confidence 0.01 Published 1999 Journal Endocrinology Section Abstract Doc Link 10579360 Disease Relevance 0.09 Pain Relevance 0.20

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox