INT85301

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Context Info
Confidence 0.52
First Reported 1999
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 4.19
Pain Relevance 4.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ndp) extracellular region (Ndp) cellular_component (Ndp)
biological_process (Ndp)
Anatomy Link Frequency
nerve 1
cortex 1
Ndp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
headache 199 100.00 Very High Very High Very High
Pain 46 100.00 Very High Very High Very High
Anterior cingulate cortex 3 99.36 Very High Very High Very High
central pain 2 99.20 Very High Very High Very High
Migraine 79 98.96 Very High Very High Very High
Pain threshold 8 95.76 Very High Very High Very High
neuralgia 1 83.68 Quite High
Anterior cingulate 3 75.00 Quite High
Cluster headache 8 5.00 Very Low Very Low Very Low
cva 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Headache 190 100.00 Very High Very High Very High
Pain 45 100.00 Very High Very High Very High
Headache Disorders 69 98.04 Very High Very High Very High
Neuralgia 1 83.68 Quite High
Hyperacusis 2 59.76 Quite High
Photophobia 2 59.16 Quite High
Vomiting 2 57.80 Quite High
Disorders Of The Lacrimal System 2 44.16 Quite Low
Ocular Toxicity (including Many Sub-types) 1 42.88 Quite Low
Primary Headache Disorders 7 36.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Rather, our evidence to date suggests that the NDP is generated by activity in the central pain pathways.
Gene_expression (generated) of NDP associated with pain and central pain
1) Confidence 0.52 Published 1999 Journal Neurophysiol Clin Section Abstract Doc Link 10587952 Disease Relevance 0.50 Pain Relevance 0.76
Hence, although the results of this experiment did not confirm our hypothesis that the NDP is generated in SI, they are consistent with the hypothesis that the NDP is generated in the supraspinal pain pathways.


Gene_expression (generated) of NDP
2) Confidence 0.48 Published 1999 Journal Clin Neurophysiol Section Body Doc Link 10616116 Disease Relevance 0.07 Pain Relevance 0
This experiment evaluated a hypothesis derived from our earlier work, namely that the NDP is generated by pain-related activity in the primary somatosensory (SI) cortex.
Gene_expression (generated) of NDP in cortex associated with pain
3) Confidence 0.48 Published 1999 Journal Clin Neurophysiol Section Abstract Doc Link 10616116 Disease Relevance 0.45 Pain Relevance 0.49
Hence, although the results of this experiment did not confirm our hypothesis that the NDP is generated in SI, they are consistent with the hypothesis that the NDP is generated in the supraspinal pain pathways.


Gene_expression (generated) of NDP
4) Confidence 0.48 Published 1999 Journal Clin Neurophysiol Section Body Doc Link 10616116 Disease Relevance 0.06 Pain Relevance 0
This study examined the effects of orienting on two pain-related components of the sural nerve-evoked somatosensory evoked potential: the NDP (80-230 ms), which is generated in part by the anterior cingulate cortex (ACCc), and SP6 (280-340 ms).
Gene_expression (generated) of NDP in nerve associated with pain and anterior cingulate cortex
5) Confidence 0.28 Published 2004 Journal Psychophysiology Section Abstract Doc Link 15318881 Disease Relevance 0.45 Pain Relevance 0.66
The ICHD-II addresses NDPH as a single diagnosis in those with a new-onset CDH that resembles CTTH.
Gene_expression (addresses) of NDPH associated with headache
6) Confidence 0.09 Published 2007 Journal J Headache Pain Section Body Doc Link PMC2793374 Disease Relevance 2.66 Pain Relevance 2.60

General Comments

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