INT8538

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.19
First Reported 1992
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 1.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA binding (Ddx5) nucleolus (Ddx5) nucleus (Ddx5)
enzyme binding (Ddx5)
Anatomy Link Frequency
dorsal 1
striatum 1
Ddx5 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
substance P 4 100.00 Very High Very High Very High
Dopamine 9 99.74 Very High Very High Very High
Dynorphin 5 99.70 Very High Very High Very High
cocaine 5 99.48 Very High Very High Very High
Nucleus accumbens 2 95.76 Very High Very High Very High
Neuropeptide 5 94.92 High High
Enkephalin 6 94.00 High High
agonist 3 91.56 High High
projection neuron 1 70.96 Quite High
antagonist 1 62.96 Quite High

|}

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Following a 7 day period of variable free access to cocaine, dynorphin and substance P mRNA levels were elevated throughout the striatum, but the increases were substantially greater in the dorsal striatum than in the nucleus accumbens.
Positive_regulation (elevated) of P mRNA in dorsal associated with nucleus accumbens, dynorphin, substance p and cocaine
1) Confidence 0.19 Published 1992 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 1374504 Disease Relevance 0 Pain Relevance 0.84
However, it induced a decreased response to dopamine D1-receptor stimulation in the substance P mRNA levels in dorsal regions of the dopamine-depleted striatum.
Positive_regulation (stimulation) of P mRNA in striatum associated with dopamine and substance p
2) Confidence 0.01 Published 2002 Journal Synapse Section Abstract Doc Link 11746728 Disease Relevance 0 Pain Relevance 0.89

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox