INT8540

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Context Info
Confidence 0.66
First Reported 1982
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 5
Total Number 9
Disease Relevance 3.99
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Serpina1a) extracellular region (Serpina1a)
Anatomy Link Frequency
Plasma 1
liver 1
Serpina1a (Mus musculus)
Pain Link Frequency Relevance Heat
abdominal pain 1 94.28 High High
Pain 5 81.76 Quite High
Angina 24 81.04 Quite High
anesthesia 1 78.80 Quite High
cytokine 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Inflammatory marker 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 80 100.00 Very High Very High Very High
Skin Cancer 2 100.00 Very High Very High Very High
Cancer 10 99.76 Very High Very High Very High
Cirrhosis 3 99.52 Very High Very High Very High
Natriuresis 16 99.36 Very High Very High Very High
Peritonitis 5 99.26 Very High Very High Very High
Pressure And Volume Under Development 2 96.96 Very High Very High Very High
Gynecological Disease 2 95.96 Very High Very High Very High
Myocardial Infarction 156 95.44 Very High Very High Very High
Abdominal Pain 1 94.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
[Spontaneous bacterial peritonitis in cirrhosis of the liver caused by alpha-1-antitrypsin deficiency (author's transl)].
Gene_expression (deficiency) of alpha-1-antitrypsin in liver associated with cirrhosis and peritonitis
1) Confidence 0.66 Published 1982 Journal Monatsschr Kinderheilkd Section Title Doc Link 6981063 Disease Relevance 1.17 Pain Relevance 0.09
Following washes, a specific SERPIN A1 rabbit antibody (Dako) was pipetted into the wells (20 ng/100 ?
Gene_expression (antibody) of SERPIN A1
2) Confidence 0.19 Published 2010 Journal Clinical Science (London, England : 1979) Section Body Doc Link PMC2999885 Disease Relevance 0.16 Pain Relevance 0
In contrast, levels of PR3–SERPIN A1 in those readmitted with recurrent AMI [482.5 (168.9–1753.9) ng/ml] were similar to those in event-free survivors.
Gene_expression (levels) of SERPIN A1
3) Confidence 0.17 Published 2010 Journal Clinical Science (London, England : 1979) Section Body Doc Link PMC2999885 Disease Relevance 0.64 Pain Relevance 0.08
Plasma levels of NT-proBNP, MPO and PR3–SERPIN A1 were normalized by log-transformation.
Gene_expression (levels) of SERPIN A1 in Plasma associated with urological neuroanatomy
4) Confidence 0.17 Published 2010 Journal Clinical Science (London, England : 1979) Section Body Doc Link PMC2999885 Disease Relevance 0.40 Pain Relevance 0
PR3–SERPIN A1 assay
Gene_expression (assay) of SERPIN A1
5) Confidence 0.17 Published 2010 Journal Clinical Science (London, England : 1979) Section Body Doc Link PMC2999885 Disease Relevance 0.20 Pain Relevance 0
Immunohistochemically, the tumor cells were positive for vimentin, CD68, alpha-1-antichymotrypsin and alpha-1-antitrypsin.
Gene_expression (positive) of alpha-1-antitrypsin associated with cancer
6) Confidence 0.07 Published 2005 Journal J. Oral Pathol. Med. Section Abstract Doc Link 15689235 Disease Relevance 0.79 Pain Relevance 0.08
Serum levels of squamous cell carcinoma antigen, carcinoembryonic antigen, CA 125, tissue polypeptide antigen, CRP, alpha 1-antitrypsin and haptoglobin were determined peri- and postoperatively in patients undergoing surgery for benign gynecological disease (n = 18) and postoperatively in women operated for cervical carcinoma (n = 23).
Spec (determined) Gene_expression (levels) of alpha 1-antitrypsin associated with gynecological disease, skin cancer and reprotox - general 1
7) Confidence 0.05 Published 1992 Journal Arch. Gynecol. Obstet. Section Abstract Doc Link 1374604 Disease Relevance 0.64 Pain Relevance 0.08
Information about the production of A1PI and results from animal studies further implicated high-molecular-weight polysaccharides associated with sucrose stabilization of the suspect lots.
Gene_expression (production) of A1PI
8) Confidence 0.02 Published 1992 Journal Am. J. Med. Section Body Doc Link 1534964 Disease Relevance 0 Pain Relevance 0
Information about the production of A1PI and results from animal studies conducted by the manufacturer were also gathered.
Gene_expression (production) of A1PI
9) Confidence 0.02 Published 1992 Journal Am. J. Med. Section Body Doc Link 1534964 Disease Relevance 0 Pain Relevance 0

General Comments

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