INT85541

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Context Info
Confidence 0.55
First Reported 1999
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.84
Pain Relevance 3.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ngf, Calca) aging (Ngf, Calca) extracellular region (Ngf, Calca)
signal transduction (Ngf) nucleus (Calca) intracellular (Calca)
Anatomy Link Frequency
sensory neurons 4
dorsal root ganglion 2
Ngf (Rattus norvegicus)
Calca (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nerve growth factor 202 100.00 Very High Very High Very High
Calcitonin gene-related peptide 201 100.00 Very High Very High Very High
qutenza 110 100.00 Very High Very High Very High
Neuropeptide 22 100.00 Very High Very High Very High
Inflammation 12 100.00 Very High Very High Very High
substance P 10 100.00 Very High Very High Very High
dorsal root ganglion 29 99.84 Very High Very High Very High
Hyperalgesia 6 92.80 High High
Eae 2 90.96 High High
Thermal hyperalgesia 6 62.08 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 10 100.00 Very High Very High Very High
Ganglion Cysts 151 99.36 Very High Very High Very High
Nociception 16 98.52 Very High Very High Very High
Hyperalgesia 14 92.80 High High
Injury 46 89.28 High High
Pain 6 35.96 Quite Low
Hypersensitivity 4 7.04 Low Low
Headache 12 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Nervous System Injury 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nerve growth factor stimulates synthesis of calcitonin gene-related peptide in dorsal root ganglion cells during sensory regeneration in capsaicin-treated rats.
Nerve growth factor Positive_regulation (stimulates) of Gene_expression (synthesis) of calcitonin gene-related peptide in dorsal root ganglion associated with ganglion cysts, dorsal root ganglion, qutenza, nerve growth factor and calcitonin gene-related peptide
1) Confidence 0.55 Published 1999 Journal Neurosci. Res. Section Title Doc Link 10605941 Disease Relevance 0.33 Pain Relevance 1.03
NGF increases the expression of the pro-inflammatory neuropeptide CGRP [13] and increases substance P (SP) and CGRP content in sensory neurons [14-17].
NGF Positive_regulation (increases) of Gene_expression (expression) of CGRP in sensory neurons associated with inflammation, nerve growth factor, neuropeptide, substance p and calcitonin gene-related peptide
2) Confidence 0.53 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC548274 Disease Relevance 0.75 Pain Relevance 1.32
NGF increases the expression of the pro-inflammatory neuropeptide CGRP [13] and increases substance P (SP) and CGRP content in sensory neurons [14-17].
NGF Positive_regulation (increases) of Gene_expression (expression) of CGRP in sensory neurons associated with inflammation, nerve growth factor, neuropeptide, substance p and calcitonin gene-related peptide
3) Confidence 0.44 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC548274 Disease Relevance 0.76 Pain Relevance 1.36

General Comments

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