INT85629

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Context Info
Confidence 0.34
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.39
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Mc1r) signal transduction (Mc1r) plasma membrane (Mc1r)
signal transducer activity (Mc1r)
Mc1r (Mus musculus)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Skin Cancer 5 91.56 High High
Cancer 2 60.68 Quite High
Metastasis 1 27.72 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The results suggest that although the activity MC1-R and tyrosinase correlate with enhanced basal as well as MSH-induced melanogenesis in metastatic/melanotic hybrids, their expression is differentially regulated, i.e., regulation of MC1-R while at transcriptional level, the TRPs are primarily regulated via post-transcriptional mechanisms in high metastatic hybrids.
Regulation (regulated) of Regulation (regulation) of MC1-R
1) Confidence 0.34 Published 1999 Journal Pigment Cell Res. Section Abstract Doc Link 10614575 Disease Relevance 0.39 Pain Relevance 0.07

General Comments

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