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Context Info
Confidence 0.01
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 1.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA processing (Rbm39) RNA binding (Rbm39) nucleus (Rbm39)
plasma membrane (Pdyn)
Pdyn (Mus musculus)
Rbm39 (Mus musculus)
Pain Link Frequency Relevance Heat
Dynorphin 15 100.00 Very High Very High Very High
Kappa opioid receptor 3 100.00 Very High Very High Very High
opioid receptor 1 94.32 High High
antagonist 3 92.68 High High
Opioid 9 92.20 High High
narcan 3 89.40 High High
nMDA receptor 4 78.28 Quite High
Spinal cord 4 75.00 Quite High
Endogenous opioid 1 25.00 Low Low
Antinociceptive 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Toxicity 3 96.00 Very High Very High Very High
Drug Induced Neurotoxicity 1 75.00 Quite High
Injury 1 31.72 Quite Low
Spinal Cord Injury 1 28.52 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This provided indirect evidence that dynorphin also stimulates kappa-opioid receptors and suggests that kappa receptor activation may be moderately neuroprotective in the presence of an excitotoxic insult.
dynorphin Positive_regulation (stimulates) of receptors associated with dynorphin and kappa opioid receptor
1) Confidence 0.01 Published 1999 Journal Exp. Neurol. Section Abstract Doc Link 10619553 Disease Relevance 0.17 Pain Relevance 1.29

General Comments

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