INT85849

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Context Info
Confidence 0.07
First Reported 1999
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 0.85
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
insular cortex 1
behavior (Homo sapiens)
Pain Link Frequency Relevance Heat
opiate 3 100.00 Very High Very High Very High
Clonidine 2 100.00 Very High Very High Very High
Endogenous opioid 2 99.20 Very High Very High Very High
agonist 1 68.92 Quite High
Transcranial magnetic stimulation 2 30.52 Quite Low
insula 2 5.56 Low Low
drug abuse 4 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cognitive Disorder 44 98.06 Very High Very High Very High
Injury 2 82.92 Quite High
Stereotypic Movement Disorder 5 76.48 Quite High
Impulse Control Disorders 4 75.00 Quite High
Sleep Disorders 4 5.00 Very Low Very Low Very Low
Drug Dependence 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Anxiety Disorder 2 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
During active decision making, risk modulates regions of lateral prefrontal cortex, parietal cortex, and anterior insular cortex (Mohr et al., 2010), all of which contribute to the adaptive control of other aspects of behavior.
Regulation (control) of behavior in insular cortex
1) Confidence 0.07 Published 2010 Journal Frontiers in Neuroscience Section Body Doc Link PMC2948450 Disease Relevance 0 Pain Relevance 0
Accordingly, a core theme of cognitive neuroscience research has been to parse PFC according to distinct sub-regionsÂ’ contributions to control of behavior.
Regulation (control) of behavior associated with cognitive disorder
2) Confidence 0.04 Published 2010 Journal Frontiers in Neuroscience Section Body Doc Link PMC2948450 Disease Relevance 0.21 Pain Relevance 0
Beneficial effects of clonidine on severe self-injurious behavior in a 9-year-old girl with pervasive developmental disorder.
Regulation (effects) of behavior associated with clonidine
3) Confidence 0.00 Published 1999 Journal J Child Adolesc Psychopharmacol Section Title Doc Link 10630459 Disease Relevance 0.16 Pain Relevance 0.21
Preliminary data about the therapeutic effect of opiate receptor manipulation in self-injurious behavior (SIB) suggest that endogenous opioid mechanisms may have a pathophysiological role in that condition and their involvement may be dependent on the severity of the SIB.
Regulation (effect) of behavior associated with endogenous opioid and opiate
4) Confidence 0.00 Published 2002 Journal Prog. Neuropsychopharmacol. Biol. Psychiatry Section Abstract Doc Link 12369265 Disease Relevance 0.48 Pain Relevance 0.35

General Comments

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