INT85861

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.21
First Reported 2000
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 1.33
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Abpe) cellular_component (Abpe) biological_process (Abpe)
Anatomy Link Frequency
lacrimal 5
lacrimal gland 1
Abpe (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 15 99.46 Very High Very High Very High
adenocard 5 97.54 Very High Very High Very High
Inflammation 5 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Cholecystokinin 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorders Of The Lacrimal System 95 100.00 Very High Very High Very High
Eyelid Disease 2 82.08 Quite High
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Dry Eye 4 5.00 Very Low Very Low Very Low
Autoimmune Disease 2 5.00 Very Low Very Low Very Low
Syndrome 2 5.00 Very Low Very Low Very Low
Acne 1 5.00 Very Low Very Low Very Low
Androgen Insensitivity 1 5.00 Very Low Very Low Very Low
Aging 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Androgens are known to exert a tremendous impact on the structure and function of the lacrimal gland, including such aspects as the cellular morphology, nuclear architecture, protein synthesis, enzyme activity, receptor expression and fluid and protein secretion [28].
Localization (secretion) of lacrimal in lacrimal gland associated with disorders of the lacrimal system
1) Confidence 0.21 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2728565 Disease Relevance 0.91 Pain Relevance 0
In separate experiments, cells were pretreated with pertussis toxin or polyclonal antibodies against the alpha subunits of Gi/Go to determine the physiologic role of G proteins in met-enkephalin inhibition of the release of lacrimal protein.
Localization (release) of lacrimal in lacrimal
2) Confidence 0.02 Published 2000 Journal Cornea Section Body Doc Link 10632016 Disease Relevance 0.08 Pain Relevance 0
RESULTS: Cch resulted in a significant increase in protein release from cultured lacrimal acini.
Localization (release) of lacrimal in lacrimal
3) Confidence 0.01 Published 2000 Journal Cornea Section Body Doc Link 10632016 Disease Relevance 0.07 Pain Relevance 0
PURPOSE: To determine whether G-protein-mediated inhibition of secretion by met-enkephalin involves cyclic adenosine monophosphate (cAMP)-dependent events and to identify the G proteins that couple met-enkephalin to inhibition of lacrimal secretion.
Localization (secretion) of lacrimal in lacrimal associated with disorders of the lacrimal system, adenocard and enkephalin
4) Confidence 0.01 Published 2000 Journal Cornea Section Abstract Doc Link 10632016 Disease Relevance 0.17 Pain Relevance 0.32
However, we suggest a role for met-enkephalin in G-protein-coupled modulation of ion channels important for cholinergic and beta-adrenergic stimulation of lacrimal secretion.


Localization (secretion) of lacrimal in lacrimal
5) Confidence 0.01 Published 2000 Journal Cornea Section Body Doc Link 10632016 Disease Relevance 0 Pain Relevance 0
Gi/Go couple met-enkephalin to inhibition of cholinergic and beta-adrenergic stimulation of lacrimal secretion.
Localization (secretion) of lacrimal in lacrimal associated with disorders of the lacrimal system and enkephalin
6) Confidence 0.01 Published 2000 Journal Cornea Section Title Doc Link 10632016 Disease Relevance 0.10 Pain Relevance 0.34

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox