INT85937

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Context Info
Confidence 0.86
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 4.31
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ALB) small molecule metabolic process (ALB) enzyme binding (ALB)
DNA binding (ALB) protein complex (ALB) transmembrane transport (ALB)
ALB (Homo sapiens)
Pain Link Frequency Relevance Heat
ischemia 10 99.36 Very High Very High Very High
cINOD 5 89.84 High High
Arthritis 3 84.56 Quite High
palliative 3 50.00 Quite Low
Inflammation 21 41.04 Quite Low
imagery 23 39.00 Quite Low
nud 2 11.24 Low Low
backache 1 7.64 Low Low
pain pelvic 1 7.20 Low Low
cva 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 89 99.98 Very High Very High Very High
Cv Unclassified Under Development 9 99.36 Very High Very High Very High
Cirrhosis 2 96.84 Very High Very High Very High
Malignant Neoplastic Disease 63 96.24 Very High Very High Very High
Asthma 5 90.96 High High
Edema 8 90.48 High High
Malignant Pleural Effusion 4 87.44 High High
Lung Injury 4 86.72 High High
Arthritis 3 84.56 Quite High
Lymphatic System Cancer 2 81.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vitro stereoselective degradation of carprofen glucuronide by human serum albumin.
Protein_catabolism (degradation) of albumin
1) Confidence 0.86 Published 2000 Journal Chirality Section Title Doc Link 10637410 Disease Relevance 0 Pain Relevance 0.09
The authors argued that formaldehyde modification led to increased negative charge to albumin molecule, which directs the molecules to scavenger receptors and subsequently to the lysosomes, the common cell surface binding pathway that mediates the uptake and degradation.
Protein_catabolism (degradation) of albumin molecule
2) Confidence 0.55 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2768759 Disease Relevance 0 Pain Relevance 0
Blomhoff et al. reported that formaldehyde-modified albumin can be internalized by scavenger receptors and degraded in lysosome, suggesting the involvement of clathrin route [35].
Protein_catabolism (degraded) of albumin
3) Confidence 0.41 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2768759 Disease Relevance 0 Pain Relevance 0
Serum to ascites albumin gradient
Protein_catabolism (gradient) of albumin associated with pressure and volume under development
4) Confidence 0.37 Published 2010 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2880345 Disease Relevance 2.80 Pain Relevance 0
It was found that (i) cell attachment and proliferation were surface roughness sensitive, and increased as the roughness of Ti-6Al-4V increased, (ii) human albumin was adsorbed preferentially onto the smooth substratum, and (iii) the rough substratum bound a higher amount of total protein (from culture medium supplied with 15% serum) and fibronectin (10-fold) than did the smooth one [59], suggesting an importance of the rugophilicity.
Protein_catabolism (was) of albumin
5) Confidence 0.12 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2871132 Disease Relevance 0.21 Pain Relevance 0
apocynin is able to maintain normal endothelial albumin permeability during
Protein_catabolism (permeability) of albumin
6) Confidence 0.07 Published 2008 Journal Mediators of Inflammation Section Body Doc Link PMC2593395 Disease Relevance 1.30 Pain Relevance 0.29

General Comments

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