INT86024
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
We found that co-expression of PPAR delta, retinoid X receptor (RXR) alpha, and coactivators such as CBP and SRC-1 enhanced basal and agonist-dependent activation of PPAR responsive element (PPRE)-driven transcription by PPAR delta, rendering a PPRE-driven reporter assay reliable and sensitive. | |||||||||||||||
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It has been shown that in inflammatory skin disorders, including hyperproliferative psoriatic epidermis and the skin of patients with atopic dermatitis, the expression of both PPARalpha and PPARgamma is decreased. | |||||||||||||||
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This observation suggests the possibility that PPARalpha and PPARgamma activators, or compounds that positively regulate PPAR gene expression, may represent novel NSAIDs for the topical or systemic treatment of common inflammatory skin diseases such as atopic dermatitis, psoriasis, and allergic contact dermatitis. | |||||||||||||||
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does not express PPAR?. | |||||||||||||||
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chosen because the first does not express PPAR? | |||||||||||||||
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This review will focus on the major studies dealing with PPAR expression in gliomas and neuroblastoma and the therapeutic implications of using PPAR agonists for the treatment of these neoplasms.
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, based on the characteristic nucleotide sequence [32], [33], on known similarities in tissue expression between ERR and PPAR? | |||||||||||||||
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gene (PPARA) expression have the potential to modify outcomes following acute coronary ischemia in patients. | |||||||||||||||
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activate PPARA expression via direct binding to PPARA promoter B (? | |||||||||||||||
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Of particular interest because of the previously established important effects of nuclear hormone receptors on PPARA expression [28], [31], was a G to A substitution located 6,862 nucleotides upstream of the major PPARA transcription start site of promoter A that disrupts a nuclear receptor half-site, designated PPARA ? | |||||||||||||||
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We took advantage of an experiment of nature, a common pair of SNPs that alter PPARA promoter activity, to demonstrate that PPARA expression level helps determine outcome after myocardial infarction and unstable angina in human subjects with DM. | |||||||||||||||
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expression of PPAR ? | |||||||||||||||
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differential expression of PPAR ? | |||||||||||||||
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The adult PPAR expression patterns have been extensively established at the mRNA | |||||||||||||||
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The enzymes necessary to convert PGD2 into prostaglandin J2 (PGJ2) are present and coexpressed with PPAR? | |||||||||||||||
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and modify the expression of PPAR target genes; but this hypothesis has to be | |||||||||||||||
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Peroxisome proliferator-activated receptor (PPAR) alpha and PPARgamma (not PPARbeta) were expressed in HASM cells. | |||||||||||||||
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Cotransfection with the PPARalpha and retinoid X receptor-alpha expression vectors and subsequent treatment with the PPARalpha agonist led to the suppression of the UGDH promoter activity either in the presence or absence of rifampicin. | |||||||||||||||
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Overexpression of PPAR? | |||||||||||||||
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The expression of PPAR? | |||||||||||||||
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