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Context Info
Confidence 0.01
First Reported 2000
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.19
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (CRTAC1) proteinaceous extracellular matrix (CRTAC1)
Anatomy Link Frequency
osteoclast 1
neural 1
CRTAC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 3 99.42 Very High Very High Very High
Pain 2 50.00 Quite Low
Cancer pain 1 5.00 Very Low Very Low Very Low
allodynia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 1 87.00 High High
Bone Cancer 2 52.44 Quite High
Cancer 2 51.04 Quite High
Pain 1 50.00 Quite Low
Osteolysis 1 49.40 Quite Low
Neuropathic Pain 1 48.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Regardless of treatment start time, OPG treatment reduced osteoclast number and tartrate-resistant acid phosphatase levels, increased bone mineral density, preserved normal bone volume and integrity on micro-computed tomography, reduced relative tumor volume in the bone, and reduced staining for glial fibrillary acidic protein in the spinal cord.
Negative_regulation (reduced) of acidic protein in osteoclast
1) Confidence 0.01 Published 2006 Journal Clin. Exp. Metastasis Section Body Doc Link 16912914 Disease Relevance 0.10 Pain Relevance 0
When septamer function was blocked by introducing septamer competitor DNA into primary differentiating neural cultures, mRNA levels of ENK, NF68, and glial fibrillary acidic protein decreased by 50-80%, whereas no effect was seen using a control DNA.
Negative_regulation (decreased) of acidic protein in neural associated with enkephalin
2) Confidence 0.00 Published 2000 Journal J. Neurosci. Section Abstract Doc Link 10648713 Disease Relevance 0.09 Pain Relevance 0.27

General Comments

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