INT86135

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Context Info
Confidence 0.25
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.67
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Ren1) extracellular space (Ren1) extracellular region (Ren1)
intracellular (Ren1) response to stress (Ren1)
Anatomy Link Frequency
glomerulus 4
afferent arteriole 2
Ren1 (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 4 73.52 Quite High
adenocard 4 71.40 Quite High
antagonist 8 67.92 Quite High
cOX1 1 42.08 Quite Low
Inflammation 3 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
beta blocker 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertension 4 93.44 High High
Targeted Disruption 6 91.20 High High
Stress 4 82.40 Quite High
Diuresis 3 80.72 Quite High
Natriuresis 3 80.20 Quite High
INFLAMMATION 5 72.08 Quite High
Chronic Renal Failure 64 71.84 Quite High
Disease 11 62.04 Quite High
Death 6 26.20 Quite Low
Increased Venous Pressure Under Development 1 25.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Many other factors are known to modify renin release and/or expression including vitamin D [13], uric acid [14], TGF?
Regulation (modify) of Localization (release) of renin
1) Confidence 0.25 Published 2010 Journal Cardiovasc Drugs Ther Section Body Doc Link PMC2887501 Disease Relevance 0.20 Pain Relevance 0
In contrast, EP4 messenger RNA is readily detected in the glomerulus where it may contribute to the regulation of renin release and decrease glomerular resistance.
Regulation (regulation) of Localization (release) of renin in glomerulus
2) Confidence 0.19 Published 2000 Journal Curr. Opin. Nephrol. Hypertens. Section Abstract Doc Link 10654821 Disease Relevance 0.49 Pain Relevance 0.07
The IP receptor messenger RNA is most highly expressed in the afferent arteriole and it may also modulate renal arterial resistance and renin release.
Regulation (modulate) of Localization (release) of renin in afferent arteriole
3) Confidence 0.09 Published 2000 Journal Curr. Opin. Nephrol. Hypertens. Section Abstract Doc Link 10654821 Disease Relevance 0.53 Pain Relevance 0.17
In contrast, EP4 receptor mRNA is predominantly expressed in the glomerulus, where it may contribute to the regulation of glomerular hemodynamics and renin release.
Regulation (regulation) of Localization (release) of renin in glomerulus
4) Confidence 0.09 Published 2001 Journal Annu. Rev. Physiol. Section Abstract Doc Link 11181968 Disease Relevance 0.45 Pain Relevance 0.11

General Comments

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