INT8621

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Context Info
Confidence 0.52
First Reported 1992
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.76
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein modification process (Padi4) nucleus (Padi4) cytoplasm (Padi4)
Anatomy Link Frequency
bladder 1
Padi4 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 25 79.16 Quite High
Hsan 1 75.00 Quite High
interstitial cystitis 2 50.00 Quite Low
fibrosis 7 14.56 Low Low
cytokine 5 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hereditary Sensory And Autonomic Neuropathies 3 100.00 Very High Very High Very High
Borrelia Infection 1 97.68 Very High Very High Very High
Diabetic Nephropathy 1 94.48 High High
Interstitial Cystitis 2 91.52 High High
INFLAMMATION 25 79.16 Quite High
Burns 10 54.32 Quite High
Keloid Scars 4 16.40 Low Low
Internal Fibrosis 1 15.04 Low Low
Fibrosis 8 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We propose that our patients may have a lower degree of expression of the genetic defect underlying HSAN type IV or that they represent a separate genetic entity.
Gene_expression (expression) of HSAN type IV associated with hereditary sensory and autonomic neuropathies
1) Confidence 0.52 Published 1992 Journal Neuropediatrics Section Abstract Doc Link 1376446 Disease Relevance 0.46 Pain Relevance 0.07
RESULTS: Selective decreases or loss of type IV collagen staining, but not laminin, were found in the UBM of 5 of 11 IC patients with no change in type IV collagen staining of other bladder wall sites.
Gene_expression (staining) of type IV in bladder
2) Confidence 0.06 Published 1995 Journal J. Urol. Section Body Doc Link 7637092 Disease Relevance 0.09 Pain Relevance 0
Besides histology, epithelial regeneration was further evaluated by immunodetection of type IV collagen ?
Gene_expression (collagen) of type IV
3) Confidence 0.04 Published 2010 Journal Molecular Vision Section Body Doc Link PMC3013068 Disease Relevance 0.20 Pain Relevance 0.08

General Comments

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