INT86257

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Context Info
Confidence 0.41
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Mention Frequency
striatum 2


Pain Term Frequency Confidence Heat
Raphe 3 100.00 Very High Very High Very High
cerebral cortex 1 98.40 Very High Very High Very High
fluoxetine 6 96.92 Very High Very High Very High
Serotonin 1 88.52 High High
Potency 1 83.76 Quite High
agonist 1 82.00 Quite High
Pyramidal cell 1 69.60 Quite High
Hippocampus 1 67.76 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, a significant decrease (-38%) in 5-HT1A mRNA levels in the anterior raphe area (but not forebrain regions) and increases in 5-HT1B mRNA levels in the striatum (+127%) and the cerebral cortex (+34%) were noted in fluoxetine-treated rats.
Negative_regulation (decrease) of Positive_regulation (increases) of 5-HT1B mRNA in striatum associated with cerebral cortex, raphe and fluoxetine
1) Confidence 0.41 Published 2000 Journal Neuropharmacology Section Abstract Doc Link 10665824 Disease Relevance 0 Pain Relevance 0.82

General Comments

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