INT86306

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Context Info
Confidence 0.01
First Reported 1999
Last Reported 1999
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 1.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Stmn1) cytosol (Stmn1) cytoskeleton (Stmn1)
intracellular (Stmn1) cytoplasm (Stmn1)
Anatomy Link Frequency
brain 1
Stmn1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Opioid 8 99.66 Very High Very High Very High
opioid receptor 8 99.22 Very High Very High Very High
orphanin 24 98.54 Very High Very High Very High
Dynorphin 2 92.64 High High
agonist 8 75.00 Quite High
antagonist 8 75.00 Quite High
Central nervous system 4 31.52 Quite Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NC does not bind to opioid receptors, and mammalian opioid peptides do not interact with the OP4 receptor.
OP4 Neg (not) Binding (interact) of associated with orphanin, opioid receptor and opioid
1) Confidence 0.01 Published 1999 Journal Farmaco Section Abstract Doc Link 10668183 Disease Relevance 0 Pain Relevance 1.06
A heptadecapeptide (Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-Leu-Ala-Asn-Gln) was identified from rat brain and from porcine brain as a ligand for OP4, a new G-protein coupled receptor that is similar in sequence to opioid receptors.
OP4 Binding (ligand) of in brain associated with opioid receptor
2) Confidence 0.01 Published 1999 Journal Farmaco Section Abstract Doc Link 10668183 Disease Relevance 0 Pain Relevance 0.62

General Comments

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