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Context Info
Confidence 0.05
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.44

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mitochondrion (PDK1) small molecule metabolic process (PDK1) carbohydrate metabolic process (PDK1)
Anatomy Link Frequency
blood 1
PDK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
alcohol 9 99.98 Very High Very High Very High
aspirin 1 96.52 Very High Very High Very High
Paracetamol 1 86.68 High High
tolerance 1 82.48 Quite High
Disease Link Frequency Relevance Heat
Disease 1 75.00 Quite High
Gastritis 1 73.36 Quite High
Alcoholic Liver Cirrhosis 1 71.32 Quite High
Alcoholic Liver Diseases 2 70.08 Quite High
Hepatic Encephalopathy 1 69.60 Quite High
Stress 1 61.28 Quite High
Toxicity 1 59.80 Quite High
Hyperuricemia 1 58.40 Quite High
Disorder Of Lipid Metabolism 1 57.76 Quite High
Hyperlipidemia 1 56.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
His work defined the role of the stomach in ethanol metabolism, description of corresponding gender differences, cloning (for the first time) of the gene for sigma ADH (a newly-recognized gastric alcohol dehydrogenase isozyme) with its chromosomal localization, and the discovery of the effects of commonly used medications (e.g., H2 blockers and aspirin) on the activities of the enzyme and on blood alcohol levels in social drinkers.
Localization (localization) of dehydrogenase isozyme in blood associated with aspirin and alcohol
1) Confidence 0.05 Published 2000 Journal Mt. Sinai J. Med. Section Abstract Doc Link 10677787 Disease Relevance 0.65 Pain Relevance 0.44

General Comments

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