INT86430

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Context Info
Confidence 0.15
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 3.61
Pain Relevance 0.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (IL6, HP) extracellular space (IL6) aging (IL6)
Anatomy Link Frequency
PGE2 4
IL6 (Homo sapiens)
HP (Homo sapiens)
Pain Link Frequency Relevance Heat
dexamethasone 2 92.92 High High
cINOD 8 75.28 Quite High
aspirin 4 73.60 Quite High
COX-2 inhibitor 2 71.76 Quite High
COX2 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Apoptosis 4 99.72 Very High Very High Very High
Cancer 24 97.92 Very High Very High Very High
Metastasis 2 97.44 Very High Very High Very High
Necrosis 2 91.80 High High
Polyps 2 88.08 High High
Hypoxia 2 87.28 High High
Targeted Disruption 2 85.12 High High
Skin Cancer 4 84.52 Quite High
Colon Cancer 2 82.16 Quite High
Familial Adenomatous Polyposis 2 78.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
COX-2 synthesizes prostaglandin E2 (PGE2) which stimulates bcl-2 and inhibits apoptosis, and induces interleukin-6 (IL-6) which enhances haptoglobin synthesis.
interleukin-6 Positive_regulation (enhances) of Gene_expression (synthesis) of haptoglobin in PGE2 associated with apoptosis
1) Confidence 0.15 Published 2000 Journal Ann. Clin. Lab. Sci. Section Abstract Doc Link 10678579 Disease Relevance 1.81 Pain Relevance 0.41
COX-2 synthesizes prostaglandin E2 (PGE2) which stimulates bcl-2 and inhibits apoptosis, and induces interleukin-6 (IL-6) which enhances haptoglobin synthesis.
IL-6 Positive_regulation (enhances) of Gene_expression (synthesis) of haptoglobin in PGE2 associated with apoptosis
2) Confidence 0.15 Published 2000 Journal Ann. Clin. Lab. Sci. Section Abstract Doc Link 10678579 Disease Relevance 1.80 Pain Relevance 0.41

General Comments

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