INT86447

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Context Info
Confidence 0.18
First Reported 2000
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.51
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Lipg) extracellular space (Lipg) extracellular region (Lipg)
lipid metabolic process (Lipg)
Anatomy Link Frequency
blood 1
Lipg (Mus musculus)
Pain Link Frequency Relevance Heat
Arthritis 12 99.52 Very High Very High Very High
Bioavailability 1 79.84 Quite High
Dopamine 5 68.28 Quite High
antagonist 12 67.48 Quite High
Serotonin 4 67.08 Quite High
Neurotransmitter 3 63.80 Quite High
Inflammation 34 50.00 Quite Low
Inflammatory response 4 49.36 Quite Low
Cannabinoid receptor 2 47.92 Quite Low
Cannabinoid 3 35.96 Quite Low
Disease Link Frequency Relevance Heat
Arthritis 28 99.52 Very High Very High Very High
Stress 13 98.24 Very High Very High Very High
Tumor Necrosis Factor Receptor-associated Periodic Syndrome 1 96.48 Very High Very High Very High
Heart Rate Under Development 6 88.64 High High
Hypotension 7 88.00 High High
Obesity 99 79.44 Quite High
INFLAMMATION 40 50.00 Quite Low
Targeted Disruption 1 49.44 Quite Low
Overweight 7 48.48 Quite Low
Weight Gain 5 39.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These findings are interpreted to indicate that exogenous 2-AG is rapidly degraded in mouse blood, probably by a lipase, which masks its ability to interact with CB1 receptors.
lipase Binding (interact) of in blood
1) Confidence 0.18 Published 2000 Journal Hypertension Section Abstract Doc Link 10679517 Disease Relevance 0.64 Pain Relevance 0.06
Both MeDL and rofecoxib maintained the
MeDL Binding (maintained) of
2) Confidence 0.05 Published 2007 Journal Mediators of Inflammation Section Body Doc Link PMC1852887 Disease Relevance 0.61 Pain Relevance 0.05
Orlistat binds irreversibly to the active sites of lipase through covalent binding.
lipase Binding (binds) of
3) Confidence 0.02 Published 2011 Journal Journal of Obesity Section Body Doc Link PMC3010692 Disease Relevance 0.26 Pain Relevance 0.14

General Comments

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