INT86460

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Context Info
Confidence 0.04
First Reported 2000
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.80
Pain Relevance 2.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
synaptic vesicles 1
Slc37a4 (Mus musculus)
Pain Link Frequency Relevance Heat
monoamine 18 100.00 Very High Very High Very High
Dopamine 268 99.98 Very High Very High Very High
cINOD 3 99.06 Very High Very High Very High
Serotonin 7 98.92 Very High Very High Very High
Dynorphin 2 91.76 High High
substance P 2 90.64 High High
Enkephalin 2 88.60 High High
dopamine receptor 5 86.72 High High
addiction 21 81.40 Quite High
depression 1 80.20 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 3 98.94 Very High Very High Very High
Depression 1 80.20 Quite High
Injury 2 79.28 Quite High
Disease 1 79.20 Quite High
Basal Ganglia Disease 2 78.04 Quite High
Myoclonus 1 76.44 Quite High
Attention Deficit Hyperactivity Disorder 1 73.88 Quite High
Sprains And Strains 94 67.64 Quite High
Targeted Disruption 11 65.96 Quite High
Stress 7 64.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This complex interaction results in transporter-dependent efflux of monoamines into extracellular space from intraneuronal stores [10,38,39].
transporter Binding (interaction) of associated with monoamine
1) Confidence 0.04 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1181539 Disease Relevance 0.11 Pain Relevance 0.62
In addition, once in the cell, amphetamines interfere with the vesicular monoamine transporter, depleting synaptic vesicles.
transporter Binding (interfere) of in synaptic vesicles associated with monoamine
2) Confidence 0.02 Published 2006 Journal PLoS Medicine Section Body Doc Link PMC1635740 Disease Relevance 0.32 Pain Relevance 0.74
Autoradiographic quantitation also showed a 30% increase in striatal dopamine transporter binding.
transporter Binding (binding) of associated with dopamine
3) Confidence 0.01 Published 2000 Journal Neuroscience Section Abstract Doc Link 10682710 Disease Relevance 0.56 Pain Relevance 0.50
In contrast to these drugs, non-steroidal anti-inflammatory drugs such as ibuprofen, ketoprofen, and fenoprofen interact with the transporter but do not serve as transportable substrates (35).
transporter Binding (interact) of associated with inflammation and cinod
4) Confidence 0.01 Published 2008 Journal AAPS J Section Body Doc Link PMC2751467 Disease Relevance 0.28 Pain Relevance 0.21
This finding establishes a link between the phosphate binding ABC transporter and the Hxc system in P. aeruginosa.
transporter Binding (binding) of
5) Confidence 0.00 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2242829 Disease Relevance 0.53 Pain Relevance 0

General Comments

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