INT86503

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Context Info
Confidence 0.09
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.49
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
monocytes 1
MALT 1
Fcer2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
spinal inflammation 2 97.20 Very High Very High Very High
headache 1 87.16 High High
Central nervous system 7 81.68 Quite High
intrathecal 1 77.52 Quite High
imagery 4 50.00 Quite Low
vincristine 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lymphatic System Cancer 23 98.28 Very High Very High Very High
Mantle-cell Lymphoma 26 98.24 Very High Very High Very High
Low Back Pain 2 97.20 Very High Very High Very High
Cranial Neuropathy 1 89.00 High High
B-cell Chronic Lymphocytic Leukemia 9 88.96 High High
Headache 1 87.16 High High
Disease 7 86.92 High High
Htlv Types I And Ii 1 83.20 Quite High
Cancer 8 77.76 Quite High
Recurrence 3 73.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pathology revealed small to medium-sized cells with a moderate amount of cytoplasm and irregular nuclear borders, expressing pan B-cell markers (CD19, CD20, and CD79a) but lacking CD10, CD23, and cyclin D1, confirming low-grade MALT lymphoma.
Negative_regulation (lacking) of CD23 in MALT associated with lymphatic system cancer
1) Confidence 0.09 Published 2009 Journal Clinical lymphoma & myeloma Section Abstract Doc Link 19525185 Disease Relevance 0.93 Pain Relevance 0.38
CD23 is negative or weakly positive.
Negative_regulation (positive) of CD23
2) Confidence 0.04 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2853553 Disease Relevance 1.38 Pain Relevance 0
OBJECTIVE: Expression of IgA Fc receptors (CD89, FcalphaR) and their occupancy by endogenous IgA were studied on blood monocytes and neutrophits to determine if FcalphaR defects could account for enhanced serum IgA and IgA-IC commonly found in patients with ankylosing spondylitis (AS).
Negative_regulation (defects) of FcalphaR in monocytes associated with spinal inflammation
3) Confidence 0.01 Published 2000 Journal J. Rheumatol. Section Abstract Doc Link 10685807 Disease Relevance 0.17 Pain Relevance 0.17

General Comments

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