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Context Info
Confidence 0.44
First Reported 2000
Last Reported 2010
Negated 1
Speculated 1
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 1.48
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Prl)
Anatomy Link Frequency
thyroid 2
Prl (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cryotherapy 5 100.00 Very High Very High Very High
Pain 2 96.32 Very High Very High Very High
Inflammation 1 94.28 High High
Opioid 1 86.00 High High
Cholecystokinin 1 83.40 Quite High
gABA 1 81.48 Quite High
Dopamine 3 81.24 Quite High
agonist 1 28.16 Quite Low
Neuropeptide 1 25.00 Low Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Prolactinoma 18 99.96 Very High Very High Very High
Pain 2 96.32 Very High Very High Very High
INFLAMMATION 1 94.28 High High
Galactorrhea 1 93.28 High High
Coronary Artery Disease 18 92.80 High High
Cancer 3 75.00 Quite High
Adenoma 1 62.00 Quite High
Sprains And Strains 1 55.32 Quite High
Adhesions 3 50.36 Quite High
Pituitary Cancer 3 30.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In E(2)-induced rat prolactinomas, prolactin mRNA contents and the expression of some proto-oncogenes, e.g. c-myc and c-ras, TGFalpha and TGFbeta1 mRNA were significantly changed.
Regulation (changed) of Transcription (expression) of prolactin mRNA associated with prolactinoma
1) Confidence 0.44 Published 2000 Journal Biol Signals Recept Section Abstract Doc Link 10686432 Disease Relevance 0.90 Pain Relevance 0.21
These results suggest that the expression of E-cadherin does not affect prolactin mRNA transcription; rather, it reduces prolactin protein content, presumably by affecting trafficking of secretory granules.

Neg (not) Regulation (affect) of Transcription (transcription) of prolactin
2) Confidence 0.21 Published 2010 Journal Acta Histochemica et Cytochemica Section Abstract Doc Link PMC2875860 Disease Relevance 0.30 Pain Relevance 0
The aim of the present study was to examine the effects of two types of cold therapy, winter swimming in ice-cold water (WS) and whole body cryotherapy (WBC), on the serum levels of the growth hormone, prolactin, thyrotropin and free fractions of thyroid hormones (fT3, fT4).
Spec (examine) Regulation (effects) of Transcription (levels) of prolactin in thyroid associated with cryotherapy
3) Confidence 0.11 Published 2009 Journal Cryobiology Section Abstract Doc Link 19444973 Disease Relevance 0.28 Pain Relevance 0.38

General Comments

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