INT86636

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.39
First Reported 2000
Last Reported 2003
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 0.83
Pain Relevance 1.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (POMC) cell-cell signaling (POMC) cytoplasm (POMC)
cell proliferation (KRT16) extracellular space (POMC) generation of precursor metabolites and energy (POMC)
Anatomy Link Frequency
skin 4
POMC (Homo sapiens)
KRT16 (Homo sapiens)
Pain Link Frequency Relevance Heat
opiate 14 100.00 Very High Very High Very High
agonist 1 97.36 Very High Very High Very High
Opioid 4 96.20 Very High Very High Very High
Neuropeptide 1 95.72 Very High Very High Very High
psoriasis 4 89.92 High High
Pain 3 28.56 Quite Low
Inflammatory response 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Wound Healing 3 98.60 Very High Very High Very High
Psoriasis 6 89.92 High High
Skin Diseases 1 84.56 Quite High
Injury 8 79.28 Quite High
Pain 2 28.56 Quite Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have previously observed that beta-endorphin, the endogenous ligand for the mu-opiate receptor, stimulates the expression of cytokeratin 16 in a dose-dependent manner in human skin organ cultures.
beta-endorphin Positive_regulation (stimulates) of Gene_expression (expression) of cytokeratin 16 in skin associated with opiate
1) Confidence 0.39 Published 2003 Journal J. Invest. Dermatol. Section Abstract Doc Link 12535211 Disease Relevance 0.51 Pain Relevance 0.62
beta-endorphin stimulates cytokeratin 16 expression and downregulates mu-opiate receptor expression in human epidermis.
beta-endorphin Positive_regulation (stimulates) of Gene_expression (expression) of cytokeratin 16 in epidermis associated with opiate
2) Confidence 0.36 Published 2000 Journal J. Invest. Dermatol. Section Title Doc Link 10692113 Disease Relevance 0.32 Pain Relevance 0.67

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox