INT86638

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Context Info
Confidence 0.34
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 0.33
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (POMC) Golgi apparatus (OPRM1) endoplasmic reticulum (OPRM1)
signal transducer activity (OPRM1) cell-cell signaling (POMC) cytoplasm (POMC)
Anatomy Link Frequency
epidermis 2
POMC (Homo sapiens)
OPRM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
opiate 8 100.00 Very High Very High Very High
Opioid 1 98.12 Very High Very High Very High
psoriasis 3 89.56 High High
Disease Link Frequency Relevance Heat
Psoriasis 5 89.56 High High
Skin Diseases 1 86.48 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
beta-endorphin stimulates cytokeratin 16 expression and downregulates mu-opiate receptor expression in human epidermis.
beta-endorphin Negative_regulation (downregulates) of Gene_expression (expression) of mu-opiate receptor in epidermis associated with opiate
1) Confidence 0.34 Published 2000 Journal J. Invest. Dermatol. Section Title Doc Link 10692113 Disease Relevance 0.33 Pain Relevance 0.68

General Comments

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