INT86669

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Context Info
Confidence 0.30
First Reported 1999
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.37
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (HOMER1) cytoplasm (HOMER1)
Anatomy Link Frequency
liver 1
synapses 1
HOMER1 (Homo sapiens)
Pain Link Frequency Relevance Heat
abdominal pain 1 94.52 High High
Bile 4 90.60 High High
Nucleus accumbens 1 82.44 Quite High
Neuropeptide 3 25.00 Low Low
Enkephalin 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Leukocytosis 1 99.80 Very High Very High Very High
Cyst 2 96.36 Very High Very High Very High
Echinococcosis 3 95.52 Very High Very High Very High
Abdominal Pain 1 94.52 High High
Fever 1 93.76 High High
Jaundice 1 93.48 High High
Emergencies 1 92.56 High High
Rupture 3 87.48 High High
Hydatid Disease 1 86.96 High High
Obstructive Jaundice 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Laboratory data of significance included an increased of liver function tests (Bilirubin, Alkaline ph., SGOT, SGPT), VES and leukocytosis.
Positive_regulation (increased) of VES in liver associated with leukocytosis
1) Confidence 0.30 Published 1999 Journal Ann Ital Chir Section Abstract Doc Link 10692798 Disease Relevance 1.31 Pain Relevance 0.26
These results (1) suggest a differential modulation of Homer by typical and atypical antipsychotics; (2) confirm that Homer can be induced as an early gene with putative direct effect on neuronal plasticity and (3) demonstrate different response to antipsychotics by different classes of postsynaptic density proteins at glutamatergic synapses.
Positive_regulation (induced) of Homer in synapses
2) Confidence 0.17 Published 2002 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 11834303 Disease Relevance 0.06 Pain Relevance 0.04

General Comments

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