INT86702

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Context Info
Confidence 0.69
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 0.76
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Cav1) mitochondrion (Cav1) Golgi apparatus (Cav1)
endoplasmic reticulum (Cav1) intracellular (Cav1) protein complex (Cav1)
Anatomy Link Frequency
arterioles 2
embryonic kidney 2
myocardium 1
fibroblasts 1
Cav1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 3 87.04 High High
ischemia 6 82.40 Quite High
IPN 1 71.40 Quite High
Inflammation 15 54.40 Quite High
COX-2 inhibitor 3 50.72 Quite High
Pain 3 47.28 Quite Low
Arthritis 3 46.64 Quite Low
Osteoarthritis 12 5.00 Very Low Very Low Very Low
addiction 6 5.00 Very Low Very Low Very Low
rheumatoid arthritis 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 1 91.44 High High
Stress 38 86.24 High High
Cv Unclassified Under Development 5 75.84 Quite High
INFLAMMATION 9 54.40 Quite High
Cytomegalovirus Infection 1 49.76 Quite Low
Pain 3 47.28 Quite Low
Arthritis 9 46.64 Quite Low
Coronary Artery Disease 1 46.00 Quite Low
Injury 1 44.32 Quite Low
Adhesions 2 6.96 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In separate rats from the same groups, we compared eNOS and caveolin-1 (CAV-1) protein abundance in pial arterioles (via immunofluorescence analyses).
Localization (abundance) of CAV-1 in arterioles
1) Confidence 0.69 Published 2000 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 10694495 Disease Relevance 0 Pain Relevance 0.09
In separate rats from the same groups, we compared eNOS and caveolin-1 (CAV-1) protein abundance in pial arterioles (via immunofluorescence analyses).
Localization (abundance) of caveolin-1 in arterioles
2) Confidence 0.69 Published 2000 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 10694495 Disease Relevance 0 Pain Relevance 0.09
It clearly documents a significant role of ROS signaling in Akt/eNOS/Cav-3-mediated GLUT-4 translocation and association in IP myocardium.
Localization (translocation) of Cav in myocardium
3) Confidence 0.60 Published 2007 Journal Am. J. Physiol. Heart Circ. Physiol. Section Abstract Doc Link 17277024 Disease Relevance 0.15 Pain Relevance 0.19
In addition, we have reported COX-1 was also co-localized with Cav-1 and Cav-2 in human embryonic kidney (HEK 293) cells (10).
Localization (localized) of Cav-1 in embryonic kidney
4) Confidence 0.36 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2733955 Disease Relevance 0.05 Pain Relevance 0.05
In addition, we have reported COX-1 was also co-localized with Cav-1 and Cav-2 in human embryonic kidney (HEK 293) cells (10).
Localization (localized) of Cav in embryonic kidney
5) Confidence 0.36 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2733955 Disease Relevance 0.05 Pain Relevance 0.05
In 2001, Liou and coworkers (9) have reported that COX-2 was co-localized with Cav-1 in human fibroblasts.
Localization (localized) of Cav-1 in fibroblasts
6) Confidence 0.36 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2733955 Disease Relevance 0 Pain Relevance 0
Due to the rapid onset of CDI in CaV1.3, tpeak,Ca often apparently occurred earlier than tpeak,Ba.
Localization (onset) of CaV1
7) Confidence 0.23 Published 2010 Journal The Journal of General Physiology Section Body Doc Link PMC2828906 Disease Relevance 0 Pain Relevance 0
Furthermore, nuclear translocation of VEGFR-2 along with caveolin-1 and eNOS was reported to occur following VEGF treatment [39].
Localization (translocation) of caveolin-1
8) Confidence 0.10 Published 2004 Journal Comp Hepatol Section Body Doc Link PMC519024 Disease Relevance 0.50 Pain Relevance 0

General Comments

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