INT86705

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.65
First Reported 1999
Last Reported 2010
Negated 8
Speculated 0
Reported most in Body
Documents 41
Total Number 41
Disease Relevance 37.29
Pain Relevance 8.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (BTG3)
Anatomy Link Frequency
muscle 2
erythrocyte 1
smooth muscle 1
liver 1
pallidum 1
BTG3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Infliximab 268 99.80 Very High Very High Very High
Inflammation 219 99.26 Very High Very High Very High
Inflammatory response 9 98.92 Very High Very High Very High
rheumatoid arthritis 528 98.68 Very High Very High Very High
spinal inflammation 183 97.64 Very High Very High Very High
Angina 6 94.68 High High
Arthritis 267 94.36 High High
Adalimumab 84 93.20 High High
psoriasis 3 91.08 High High
abdominal pain 10 89.40 High High
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 529 100.00 Very High Very High Very High
Systemic Lupus Erythematosus 173 100.00 Very High Very High Very High
Trepenoma Infection 2 100.00 Very High Very High Very High
Autoimmune Hepatitis 792 99.92 Very High Very High Very High
Pulmonary Disease 170 99.80 Very High Very High Very High
Viral Infection 18 99.80 Very High Very High Very High
Rheumatic Diseases 24 99.64 Very High Very High Very High
Seronegative Spondarthritis 79 99.44 Very High Very High Very High
INFLAMMATION 237 99.26 Very High Very High Very High
Occupational Lung Diseases 38 99.06 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Laboratory measurements included complete blood count, erythrocyte sedimentation rate (ESR), C reactive protein (CRP), total protein and albumin, blood and urine electrolytes, immunoglobulins (IgA, IgG, IgM), C3, C4, ASO, ANA, anti-DNA, Ra test, p-ANCA, blood urea nitrogen (BUN), creatinine, culture of pharyngeal swabbing and stool guiac test and routine urinalysis (which was performed every 15 days during the study period).
Gene_expression (test) of ANA in erythrocyte associated with rheumatoid arthritis
1) Confidence 0.65 Published 2008 Journal BMC Pediatr Section Body Doc Link PMC2542358 Disease Relevance 0.41 Pain Relevance 0.04
IL-10, and autoantibodies (ANA, ACA, anti-dsDNA, and anti-HTG) were measured in serum samples collected from 14 of the 22 patients with melanoma undergoing IFN-?
Gene_expression (measured) of ANA associated with skin cancer
2) Confidence 0.65 Published 2010 Journal J Transl Med Section Body Doc Link PMC2936304 Disease Relevance 0.36 Pain Relevance 0
Of the 56 patients, ANA titers were positive in 52 (93%) and negative in only 4 (7%) of them.
Neg (negative) Gene_expression (negative) of ANA
3) Confidence 0.61 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2861942 Disease Relevance 1.60 Pain Relevance 0.42
ANA, anti-DNA, p-ANCA and c-ANCA were all negative.
Neg (negative) Gene_expression (negative) of ANA
4) Confidence 0.58 Published 2007 Journal Rheumatol. Int. Section Abstract Doc Link 16972085 Disease Relevance 0.81 Pain Relevance 0.09
Additional investigations, including ANA, ANCA, and serological testing for syphilis were negative.
Neg (negative) Gene_expression (negative) of ANA associated with trepenoma infection
5) Confidence 0.58 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2350140 Disease Relevance 0.95 Pain Relevance 0.29
Both cases were complicated by silicosis and the laboratory findings showed high serum levels of P-ANCA, ANA and rheumatoid factor and inflammatory responses, indicating they were suspected vasculitis.
Gene_expression (levels) of ANA associated with inflammatory response, increased venous pressure under development and occupational lung diseases
6) Confidence 0.47 Published 1999 Journal Ryumachi Section Abstract Doc Link 10695408 Disease Relevance 2.07 Pain Relevance 0.26
Detection of ANA
Gene_expression (Detection) of ANA
7) Confidence 0.40 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526573 Disease Relevance 0 Pain Relevance 0.07
Clinical monitoring of the subgroup of patients positive for ANA and anti-dsDNA autoantibodies did not show any manifestation potentially related to a full-blown lupus disease.
Gene_expression (autoantibodies) of ANA associated with disease and systemic lupus erythematosus
8) Confidence 0.40 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526573 Disease Relevance 0.53 Pain Relevance 0.35
The presence of anti-nuclear antibody (ANA) deliberates risk for the development of asymptomatic uveitis, particularly in those individuals with oligoarticular onset disease, although assessment of ANA should be performed in all JIA patients14, 15).
Gene_expression (presence) of ANA associated with disease, uveitis and arthritis
9) Confidence 0.34 Published 2010 Journal Korean Journal of Pediatrics Section Body Doc Link PMC3012272 Disease Relevance 1.37 Pain Relevance 0.30
Detection of ANA
Gene_expression (Detection) of ANA
10) Confidence 0.34 Published 2004 Journal Arthritis Res Ther Section Body Doc Link PMC1064868 Disease Relevance 0.81 Pain Relevance 0.67
Rheumatoid factor, CCP antibodies, ANA, and HLA-B27 were negative and/or normal.
Neg (negative) Gene_expression (negative) of ANA
11) Confidence 0.31 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2902413 Disease Relevance 1.12 Pain Relevance 0.30
After 2 years of infliximab therapy, ANA became positive in one other infliximab-treated RA patient and three more AS patients, giving a total induction of 87% in RA and 85% in AS.
Gene_expression (positive) of ANA associated with spinal inflammation, infliximab and rheumatoid arthritis
12) Confidence 0.30 Published 2004 Journal Arthritis Res Ther Section Body Doc Link PMC1064868 Disease Relevance 2.01 Pain Relevance 1.66
All patients who became positive for anti-dsDNA autoantibodies were also positive for ANA.
Gene_expression (positive) of ANA
13) Confidence 0.30 Published 2004 Journal Arthritis Res Ther Section Body Doc Link PMC1064868 Disease Relevance 1.38 Pain Relevance 1.21
In both groups, the ANA scores and titers were highly correlated, suggesting that the scoring provides a close estimation of titer (Missoula: correlation coefficient = 0.502, p < 0.001; Libby: correlation coefficient = 0.828, p < 0.001; Table 3).
Gene_expression (scores) of ANA
14) Confidence 0.22 Published 2005 Journal Environ Health Perspect Section Body Doc Link PMC1253705 Disease Relevance 0 Pain Relevance 0
This possibility is supported by the lack of correlation between IgA titers and either ANA or asbestos exposure; however, a correlation between IgA titers and disease status was also lacking in our analysis.
Gene_expression (exposure) of ANA associated with disease
15) Confidence 0.22 Published 2005 Journal Environ Health Perspect Section Body Doc Link PMC1253705 Disease Relevance 0.69 Pain Relevance 0.20
Samples with positive ANAs were also evaluated using a modified ANA test to determine whether any of the anti-ANA antibodies were of the IgA isotype.
Gene_expression (antibodies) of ANA
16) Confidence 0.22 Published 2005 Journal Environ Health Perspect Section Body Doc Link PMC1253705 Disease Relevance 0.05 Pain Relevance 0
Alternatively, because there were positive correlations between RF and both ANA titer and ARD, the threshold of asbestos exposure impacting development of RF may simply be too low to be detected using the simplified exposure scale (Table 2).
Gene_expression (titer) of ANA associated with pulmonary disease
17) Confidence 0.22 Published 2005 Journal Environ Health Perspect Section Body Doc Link PMC1253705 Disease Relevance 0.70 Pain Relevance 0.17
We demonstrated that the autoantibodies detected by ANA were not of the IgA isotype, so it is possible that the IgA antibodies are simply elicited by nonspecific chronic inflammatory processes in these individuals.
Gene_expression (detected) of ANA associated with inflammation
18) Confidence 0.22 Published 2005 Journal Environ Health Perspect Section Body Doc Link PMC1253705 Disease Relevance 0.74 Pain Relevance 0.22
The ANA tests were subsequently modified to detect IgA rather than IgG, and all of the ANA tests were negative in both sample sets, indicating that the autoantibodies were most likely primarily IgG and not IgA (data not shown).
Gene_expression (detect) of ANA
19) Confidence 0.22 Published 2005 Journal Environ Health Perspect Section Body Doc Link PMC1253705 Disease Relevance 0.13 Pain Relevance 0.07
All autoantibodies including ANA, cANCA, pANCA were negative, serum ACE was within normal limits, no antibodies were found against treponema pallidum and borrelia bergdorfi.
Neg (negative) Gene_expression (negative) of ANA in pallidum
20) Confidence 0.20 Published 2008 Journal Cases J Section Body Doc Link PMC2602997 Disease Relevance 1.00 Pain Relevance 0.13

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox