INT86712

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Context Info
Confidence 0.15
First Reported 2000
Last Reported 2003
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 2.03
Pain Relevance 1.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Tgfb1) enzyme binding (Tgfb1) embryo development (Tgfb1)
cytoplasm (Tgfb1) cell proliferation (Tgfb1) extracellular space (Tgfb1)
Anatomy Link Frequency
osteoblast 2
Tgfb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 4 100.00 Very High Very High Very High
acular 4 100.00 Very High Very High Very High
Chronic pancreatitis 10 99.66 Very High Very High Very High
fibrosis 5 99.18 Very High Very High Very High
cINOD 6 94.44 High High
Inflammation 2 63.04 Quite High
Disease Link Frequency Relevance Heat
Pancreatitis 12 100.00 Very High Very High Very High
Fibrosis 6 99.18 Very High Very High Very High
Osteoporosis 5 97.88 Very High Very High Very High
Body Weight 2 95.44 Very High Very High Very High
Apoptosis 2 92.28 High High
INFLAMMATION 4 76.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Transforming growth factor-beta1 (TGF-beta1) is suggested to be a mediator of fibrosis in chronic pancreatitis, but the serial change of TGF-beta1 expression in the onset and progression of chronic pancreatitis is still unclear.
Regulation (change) of Gene_expression (expression) of TGF-beta1 associated with fibrosis and chronic pancreatitis
1) Confidence 0.15 Published 2000 Journal Dig. Dis. Sci. Section Abstract Doc Link 10695628 Disease Relevance 0.53 Pain Relevance 0.45
We tested the effects of ketorolac and indomethacin on the expression of TGF-beta1 mRNA and protein and the bioactivity of TGF-beta in osteoblast-enriched cultures derived from fetal calvaria.
Regulation (effects) of Gene_expression (expression) of TGF-beta1 in osteoblast associated with acular and osteoporosis
2) Confidence 0.08 Published 2003 Journal Kaohsiung J. Med. Sci. Section Abstract Doc Link 12873036 Disease Relevance 0.68 Pain Relevance 0.64
The aim of this study was to analyze the effect of CM on the gene expressions of pancreatitis-associated protein (PAP), p8, and cytokines such as interleukin-6 and transforming growth factor-beta1 in spontaneous CP model (WBN/Kob rats).
Spec (analyze) Regulation (effect) of Spec (analyze) Gene_expression (expressions) of transforming growth factor-beta1 associated with pancreatitis, chronic pancreatitis and cytokine
3) Confidence 0.05 Published 2001 Journal Pancreas Section Abstract Doc Link 11484915 Disease Relevance 0.83 Pain Relevance 0.57

General Comments

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