INT86823

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Context Info
Confidence 0.19
First Reported 2000
Last Reported 2008
Negated 0
Speculated 1
Reported most in Title
Documents 3
Total Number 3
Disease Relevance 1.48
Pain Relevance 1.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (PTGS2) endoplasmic reticulum (PTGS2) enzyme binding (PTGS2)
protein complex (PTGS2) cytoplasm (PTGS2) lipid binding (PTGS2)
PTGS2 (Homo sapiens)
Pain Link Frequency Relevance Heat
COX2 4 100.00 Very High Very High Very High
cINOD 22 99.84 Very High Very High Very High
Inflammation 1 99.00 Very High Very High Very High
aspirin 6 90.16 High High
COX-2 inhibitor 1 60.08 Quite High
Disease Link Frequency Relevance Heat
Skin Cancer 11 100.00 Very High Very High Very High
INFLAMMATION 5 99.12 Very High Very High Very High
Colon Cancer 2 87.88 High High
Cancer 5 81.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To investigate cyclooxygenase-2 (COX-2) mRNA expression in human esophageal squamous cell carcinoma and the effect of a non-steroidal anti-inflammatory drug (NSAID) on it, in order to explore the mechanism of COX-2 in esophageal squamous cell carcinoma (ESCC) carcinogenesis and the ability of NSAID to prevent or treat ESCC.
Regulation (effect) of Spec (investigate) Transcription (expression) of cyclooxygenase-2 associated with inflammation, cinod and skin cancer
1) Confidence 0.19 Published 2008 Journal Dis. Esophagus Section Abstract Doc Link 18197933 Disease Relevance 0.77 Pain Relevance 0.38
Transcriptional regulation of cyclooxygenase-2 gene expression: novel effects of nonsteroidal anti-inflammatory drugs.
Regulation (regulation) of Transcription (Transcriptional) of cyclooxygenase-2 associated with inflammation, cinod and cox2
2) Confidence 0.01 Published 2000 Journal Cancer Res. Section Title Doc Link 10706128 Disease Relevance 0.35 Pain Relevance 0.51
Transcriptional regulation of cyclooxygenase-2 gene expression: novel effects of nonsteroidal anti-inflammatory drugs.
Regulation (effects) of Transcription (Transcriptional) of cyclooxygenase-2 associated with inflammation, cinod and cox2
3) Confidence 0.01 Published 2000 Journal Cancer Res. Section Title Doc Link 10706128 Disease Relevance 0.36 Pain Relevance 0.51

General Comments

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