INT86957

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Context Info
Confidence 0.55
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 6
Disease Relevance 2.61
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Peo1) helicase activity (Peo1)
Anatomy Link Frequency
Poly 1
colon 1
bowels 1
body 1
Peo1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 44 99.26 Very High Very High Very High
backache 3 93.40 High High
Inflammation 112 86.92 High High
IPN 1 62.16 Quite High
agonist 4 46.16 Quite Low
Inflammatory mediators 4 11.12 Low Low
Crohn's disease 16 5.00 Very Low Very Low Very Low
chemokine 12 5.00 Very Low Very Low Very Low
Piles 8 5.00 Very Low Very Low Very Low
aspirin 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colitis 76 99.48 Very High Very High Very High
Body Weight 20 97.08 Very High Very High Very High
Disease 60 96.80 Very High Very High Very High
Hemorrhage 20 94.08 High High
Low Back Pain 3 93.40 High High
INFLAMMATION 108 86.92 High High
Inflammatory Bowel Disease 152 86.80 High High
Mucositis 8 82.64 Quite High
Diarrhoea 8 77.80 Quite High
Pressure And Volume Under Development 9 73.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Qualitative differences were widespread among the bowels of both the PEO (Fig 2E) and 5-ASA (Fig 2F) groups relative to the DSS group (Fig 2D).
Gene_expression (bowels) of PEO in bowels
1) Confidence 0.55 Published 2010 Journal BMC Chem Biol Section Body Doc Link PMC2881005 Disease Relevance 0.08 Pain Relevance 0.04
Therefore PEO was selected as the main observation tool in further analysis of children's sitting posture in schools in South-East England as part of a large research programme investigating back pain amongst schoolchildren.
Gene_expression (selected) of PEO associated with backache
2) Confidence 0.52 Published 2002 Journal Appl Ergon Section Abstract Doc Link 12160340 Disease Relevance 0.24 Pain Relevance 0.24
The effects of the reference drug 5-ASA (also known as mesalamine) administered at a dose of 50 mg/kg [22], produced comparable DAI to that of PEO in the acute model (Fig 1A) but were less pronounced in the chronic model (Fig 1B).
Gene_expression (produced) of PEO
3) Confidence 0.48 Published 2010 Journal BMC Chem Biol Section Body Doc Link PMC2881005 Disease Relevance 0.68 Pain Relevance 0.07
The PEO treatments significantly suppressed DSS-induced colitis in acute as well as chronic models, improving their body weights and stool consistency, as well as decreasing their intestinal bleeding (combined together as DAI, Fig 1).
Gene_expression (suppressed) of PEO in body associated with colitis, body weight and hemorrhage
4) Confidence 0.48 Published 2010 Journal BMC Chem Biol Section Body Doc Link PMC2881005 Disease Relevance 1.23 Pain Relevance 0.11
There was also a marked reduction in cytokine production in the mid colon for the PEO group (p = 0.06) (Fig 3).
Gene_expression (group) of PEO in colon associated with cytokine
5) Confidence 0.48 Published 2010 Journal BMC Chem Biol Section Body Doc Link PMC2881005 Disease Relevance 0.31 Pain Relevance 0.26
Poly(ethylene oxide) (PEO)-grafted polyurethane (PU)/polystyrene (PS) interpenetrating polymer networks (IPNs) were synthesized.
Gene_expression (synthesized) of PEO in Poly
6) Confidence 0.47 Published 2000 Journal J Biomater Sci Polym Ed Section Abstract Doc Link 10718479 Disease Relevance 0.07 Pain Relevance 0.06

General Comments

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