INT86999

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Context Info
Confidence 0.44
First Reported 2000
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.85
Pain Relevance 2.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (DYNLL1) transport (DYNLL1) mitochondrion (DYNLL1)
plasma membrane (DYNLL1) cytoskeleton (DYNLL1) nucleus (DYNLL1)
Anatomy Link Frequency
blood 1
nerve 1
DYNLL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 14 99.72 Very High Very High Very High
Restless leg syndrome 7 99.56 Very High Very High Very High
Hyperalgesia 9 98.40 Very High Very High Very High
agonist 9 92.24 High High
allodynia 2 88.48 High High
Brush evoked pain 1 75.00 Quite High
substance P 3 71.24 Quite High
nociceptor 1 70.80 Quite High
central sensitization 1 69.68 Quite High
Adelta 2 69.40 Quite High
Disease Link Frequency Relevance Heat
Pain 11 99.72 Very High Very High Very High
Restless Legs Syndrome 7 99.56 Very High Very High Very High
Injury 13 99.32 Very High Very High Very High
Hyperalgesia 9 98.40 Very High Very High Very High
Infection 9 95.88 Very High Very High Very High
Stress 11 90.68 High High
Neuropathic Pain 6 88.48 High High
Sleep Disorders 1 75.00 Quite High
Increased Venous Pressure Under Development 21 72.92 Quite High
Pseudarthrosis 1 70.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Eight patients experienced superficial pin-track infections that were easily controlled with oral antibiotics.
Regulation (controlled) of pin
1) Confidence 0.44 Published 2008 Journal J Hand Surg Am Section Body Doc Link 18261660 Disease Relevance 0.13 Pain Relevance 0
Pin screws should be controlled with meticulous wound dressing and tightened regularly to prevent pin site problems (pin loosening or infection).
Regulation (controlled) of Pin associated with injury and infection
2) Confidence 0.36 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2908866 Disease Relevance 0.40 Pain Relevance 0
CONCLUSIONS: We found a positive effect of recombinant human nerve growth factor on neuropathic pain and pin sensitivity in HIV-associated sensory neuropathy. rhNGF was safe and well tolerated, but injection site pain was frequent.


Regulation (sensitivity) of pin in nerve
3) Confidence 0.26 Published 2000 Journal Neurology Section Body Doc Link 10720278 Disease Relevance 0 Pain Relevance 0
Acute single-dose dopaminergic treatment with 100 mg levodopa + 25 mg benserazide, 90 min prior to the evening measurements, largely resolved patients' RLS symptoms, but had no effect on pin-prick pain.
Neg (no) Regulation (effect) of pin associated with pain and restless leg syndrome
4) Confidence 0.26 Published 2004 Journal Brain Section Abstract Doc Link 14985260 Disease Relevance 1.96 Pain Relevance 2.07
Neuronal Nitric Oxide Synthase and Human Vascular Regulation

Vascular blood flow and its distribution among different vascular beds are regulated by changes in microvascular tone.

Regulation (regulated) of Neuronal Nitric Oxide Synthase in blood
5) Confidence 0.07 Published 2009 Journal Trends in Cardiovascular Medicine Section Title Doc Link PMC2984617 Disease Relevance 0.37 Pain Relevance 0.11

General Comments

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