INT87024

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Context Info
Confidence 0.05
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.81
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (ZAK) response to stress (ZAK) cytoplasm (ZAK)
cell proliferation (ZAK) extracellular space (IFNG) cell death (ZAK)
Anatomy Link Frequency
T-helper cell 6
ZAK (Homo sapiens)
IFNG (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 7 100.00 Very High Very High Very High
Opioid 4 98.12 Very High Very High Very High
Dynorphin 2 94.72 High High
opioid receptor 1 57.52 Quite High
Kappa opioid receptor 1 39.44 Quite Low
Disease Link Frequency Relevance Heat
Cancer 8 75.00 Quite High
Virus Diseases 3 75.00 Quite High
Immunodeficiency 1 75.00 Quite High
Stress 1 74.24 Quite High
Bacterial Infection 2 70.24 Quite High
Hematological Disease 4 64.72 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 25.00 Low Low
Lymphopenia 1 25.00 Low Low
Renal Cancer 1 25.00 Low Low
Breast Cancer 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of MLT receptors enhances the release of T-helper cell cytokines, such as gamma-interferon and interleukin-2 (IL-2), as well as activation of novel opioid cytokines which crossreact immunologically with both interleukin-4 and dynorphin B.
Positive_regulation (Activation) of MLT in T-helper cell Positive_regulation (enhances) of Localization (release) of gamma-interferon in T-helper cell associated with dynorphin, opioid and cytokine
1) Confidence 0.05 Published 1999 Journal Adv. Exp. Med. Biol. Section Abstract Doc Link 10721059 Disease Relevance 0.49 Pain Relevance 0.33
Activation of MLT receptors enhances the release of T-helper cell type 1 (Th1) cytokines, such as gamma-interferon and interleukin-2 (IL-2), as well as of novel opioid cytokines which crossreact immunologically with both interleukin-4 (IL-4) and dynorphin B.
Positive_regulation (Activation) of MLT in T-helper cell Positive_regulation (enhances) of Localization (release) of gamma-interferon in T-helper cell associated with dynorphin, opioid and cytokine
2) Confidence 0.02 Published 1999 Journal Adv. Exp. Med. Biol. Section Abstract Doc Link 10810540 Disease Relevance 0.32 Pain Relevance 0.24

General Comments

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