INT87169

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Context Info
Confidence 0.11
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Creb1, Nkx1-1) nucleoplasm (Creb1) mitochondrion (Creb1)
nucleolus (Creb1) DNA binding (Creb1) neurological system process (Nkx1-1)
Anatomy Link Frequency
spinal 2
Creb1 (Rattus norvegicus)
Nkx1-1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Lasting pain 1 99.28 Very High Very High Very High
Spinal cord 2 87.40 High High
adenocard 1 66.80 Quite High
Pain 1 25.00 Low Low
nociceptor 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Pain 1 98.84 Very High Very High Very High
Nociception 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data support the hypothesis that transcription factor pCREB contributes to increased expression of spinal NK1 receptors during persistent pain.
pCREB Positive_regulation (contributes) of Gene_expression (expression) of NK1 in spinal associated with pain and lasting pain
1) Confidence 0.11 Published 2000 Journal Neurosci. Lett. Section Abstract Doc Link 10729626 Disease Relevance 0.17 Pain Relevance 0.21

General Comments

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