INT87196

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Context Info
Confidence 0.45
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.70
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Hmgcr) aging (Hmgcr) endoplasmic reticulum (Hmgcr)
embryo development (Hmgcr)
Anatomy Link Frequency
fat 1
Hmgcr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Angina 1 94.08 High High
imagery 1 89.28 High High
cINOD 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Dismenorea 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperlipidemia 18 97.60 Very High Very High Very High
Cv General 3 Under Development 1 94.08 High High
Myocardial Infarction 1 93.16 High High
Disorder Of Lipid Metabolism 24 90.08 High High
Coronary Artery Disease 6 88.80 High High
INFLAMMATION 4 50.00 Quite Low
Ulcers 1 50.00 Quite Low
Body Weight 6 44.48 Quite Low
Peripheral Arterial Disease 5 42.00 Quite Low
Atherosclerosis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
METHODS: The effects of three HMG-CoA reductase inhibitors, fluvastatin, pravastatin and atorvastatin on ileal ulcer formation in 5-bromo-2-(4-fluorophenyl)-3-(4- methylsulfonylphenyl) thiophene (BFMeT)-treated rats were examined.
Regulation (effects) of HMG-CoA reductase
1) Confidence 0.45 Published 2005 Journal World J. Gastroenterol. Section Body Doc Link 15742411 Disease Relevance 0 Pain Relevance 0
Effect of long-term cholesterol-lowering treatment with HMG-CoA reductase inhibitor (simvastatin) on myocardial perfusion evaluated by thallium-201 single photon emission computed tomography.
Regulation (Effect) of HMG-CoA reductase
2) Confidence 0.36 Published 2000 Journal Jpn. Circ. J. Section Title Doc Link 10732848 Disease Relevance 0.44 Pain Relevance 0.14
Doses of 200 and 400 mg/kg of the extract were evaluated for its effect on lipid profile, HMG-CoA reductase, and on antioxidant enzymes in high-fat diet (HFD) induced hyperlipidemia.


Regulation (effect) of HMG-CoA reductase in fat associated with hyperlipidemia
3) Confidence 0.10 Published 2010 Journal Journal of Pharmacy and Bioallied Sciences Section Abstract Doc Link PMC2996074 Disease Relevance 0.26 Pain Relevance 0

General Comments

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