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Context Info
Confidence 0.47
First Reported 2000
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.20
Pain Relevance 1.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (KRIT1) protein complex (KRIT1)
Anatomy Link Frequency
plasma 1
KRIT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 1 99.92 Very High Very High Very High
Opioid 14 99.32 Very High Very High Very High
agonist 1 96.92 Very High Very High Very High
headache 2 96.00 Very High Very High Very High
cva 1 94.12 High High
Morphine 1 76.08 Quite High
opioid receptor 2 74.28 Quite High
withdrawal 1 56.60 Quite High
Central nervous system 2 18.88 Low Low
Glutamate 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 2 99.44 Very High Very High Very High
Death 1 96.76 Very High Very High Very High
Stroke 3 96.40 Very High Very High Very High
Headache 2 96.00 Very High Very High Very High
Hemorrhage 1 94.12 High High
Vascular Malformations 1 92.48 High High
Neuroblastoma 1 83.40 Quite High
Apoptosis 9 83.20 Quite High
Stress 1 74.08 Quite High
Adhesions 2 73.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The encoded CCM proteins interact with each other within a large protein complex.
CCM Binding (interact) of
1) Confidence 0.47 Published 2010 Journal FEBS J. Section Abstract Doc Link 20096036 Disease Relevance 0.65 Pain Relevance 0.14
CaM was previously shown to bind directly to the OP3 receptor and to be released from the plasma membrane on agonist stimulation.
CaM Binding (bind) of in plasma associated with agonist and opioid
2) Confidence 0.35 Published 2000 Journal J. Neurochem. Section Abstract Doc Link 10737597 Disease Relevance 0.08 Pain Relevance 1.31
Recently, we showed that all three CCM proteins (Krit1, OSM, and PDCD10) form a complex in the cell and that PDCD10 binds directly to OSM independently of the OSM-Krit1 interaction [28].
Krit1 Binding (interaction) of
3) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2909203 Disease Relevance 0.47 Pain Relevance 0.03
For example, Ono et al. (2001) [15] attempt to handle the nominalizations interaction, association, and binding, and the relational noun complex (e.g.
interaction Binding (binding) of
4) Confidence 0.01 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2527518 Disease Relevance 0 Pain Relevance 0

General Comments

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