INT87294

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Context Info
Confidence 0.25
First Reported 2000
Last Reported 2000
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (SERPINA3, PTGS2) small molecule metabolic process (PTGS2) endoplasmic reticulum (PTGS2)
intracellular (SERPINA3) enzyme binding (PTGS2) DNA binding (SERPINA3)
SERPINA3 (Homo sapiens)
PTGS2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 6 99.98 Very High Very High Very High
COX-2 inhibitor 1 91.44 High High
aspirin 4 86.08 High High
COX2 1 25.00 Low Low
cOX1 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Colon Cancer 4 97.52 Very High Very High Very High
Apoptosis 3 96.44 Very High Very High Very High
INFLAMMATION 2 94.12 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It remains unclear whether individual NSAIDs act by cyclooxygenase-2 (COX-2) inhibition and how NSAIDs exert their anti-proliferative effects.
act Spec (whether) Negative_regulation (inhibition) of cyclooxygenase-2 associated with cinod
1) Confidence 0.25 Published 2000 Journal Eur. J. Cancer Section Abstract Doc Link 10738133 Disease Relevance 0.60 Pain Relevance 0.58

General Comments

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