INT87305

Context Info Confidence 0.37 First Reported 2000 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0.95 Pain Relevance 0.44

extracellular space (Cxcl1) extracellular region (Cxcl1)

Cxcl1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat cytokine 20 94.52 Inflammation 53 87.52 Bile 7 69.44 cINOD 3 58.36 ischemia 1 55.96 antagonist 1 17.68 substance P 6 5.00 chemokine 6 5.00 Neuropeptide 5 5.00 Pain 5 5.00

Disease Link Frequency Relevance Heat Acid Reflux 18 99.18 Adhesions 6 92.60 INFLAMMATION 48 87.52 Esophageal Disease 20 75.04 Gastroesophageal Reflux Disease 45 60.00 Cv Unclassified Under Development 1 55.96 Injury 4 52.84 Stress 20 50.00 Apoptosis 1 34.88 Coagulation Disorder 1 8.48

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Furthermore mRNA expression of each CINC was inhibited by dexamethasone in a dose-dependent manner.

Negative_regulation (inhibited) of Transcription (expression) of CINC

1) Confidence 0.37 Published 2000 Journal Inflamm. Res. Section Body Doc Link 10738946 Disease Relevance 0.07 Pain Relevance 0

We previously reported that in a rat model of mixed reflux esophagitis, intraduodenal rebamipide significantly inhibited the increased expression of mRNA and protein for CINC-1 and TNF-?

Negative_regulation (inhibited) of Transcription (expression) of CINC-1 associated with acid reflux

2) Confidence 0.13 Published 2007 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2291500 Disease Relevance 0.87 Pain Relevance 0.44

General Comments

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