INT8734

Context Info Confidence 0.01 First Reported 1992 Last Reported 1992 Negated 0 Speculated 0 Reported most in Title Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 1.54

cytoplasm (Pebp1, Oprd1) mitochondrion (Pebp1) aging (Pebp1) Golgi apparatus (Pebp1) signal transducer activity (Oprd1) response to stress (Pebp1)

Anatomy Link Frequency nucleus 1 Pebp1 (Rattus norvegicus) Oprd1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Morphine 11 100.00 substance P 11 100.00 opioid receptor 6 100.00 antagonist 5 89.88 Kappa opioid receptor 2 61.92 Delta opioid receptors 2 44.92

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Morphine produces a multiphasic effect on the release of substance P from rat trigeminal nucleus slices by activating different opioid receptor subtypes.

Morphine Positive_regulation (activating) of opioid receptor in nucleus associated with opioid receptor, substance p and morphine

1) Confidence 0.01 Published 1992 Journal Brain Res. Section Title Doc Link 1378347 Disease Relevance 0 Pain Relevance 1.54

General Comments

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