INT8735

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Context Info
Confidence 0.00
First Reported 1992
Last Reported 1992
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Oprm1) plasma membrane (Oprm1) transmembrane transport (Scn4a)
signal transducer activity (Oprm1)
Oprm1 (Mus musculus)
Scn4a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 11 100.00 Very High Very High Very High
substance P 11 100.00 Very High Very High Very High
Kappa opioid receptor 2 99.60 Very High Very High Very High
Delta opioid receptors 2 99.32 Very High Very High Very High
opioid receptor 6 82.52 Quite High
antagonist 5 77.76 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, the increase in SP release produced by 100 nM may be mediated by the simultaneous stimulation of beta-FNA-sensitive mu- and excitatory delta-opioid receptors whereas the facilitation of SP release induced by 30 microM MOR could be due to the activation of kappa-opioid receptors. 1 nM and 3 microM MOR may inhibit SP release by stimulating naloxonazine-sensitive mu 1- and inhibitory delta-opioid receptors, respectively.
MOR Positive_regulation (stimulating) of mu 1 associated with kappa opioid receptor, delta opioid receptors, morphine and substance p
1) Confidence 0.00 Published 1992 Journal Brain Res. Section Abstract Doc Link 1378347 Disease Relevance 0 Pain Relevance 1.49

General Comments

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