INT87528

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Context Info
Confidence 0.41
First Reported 2000
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PSMC6) nucleoplasm (PSMC6) small molecule metabolic process (PSMC6)
ATPase activity (PSMC6) nucleus (PSMC6) protein binding, bridging (PSMC6)
PSMC6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 1 25.00 Low Low
Neuropeptide 1 25.00 Low Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nicotine Addiction 2 5.00 Very Low Very Low Very Low
Adenocarcinoma 2 5.00 Very Low Very Low Very Low
Pancreatitis 1 5.00 Very Low Very Low Very Low
Pancreatic Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In dissociated astroglial cells, inhibition of protein kinase A, of p44,42 mitogen-activated protein kinase as well as of the EGF-receptor tyrosine kinase by H89, PD98059 and AG1478, respectively, reduced the PACAP38-induced expression in a synergistic manner.
Negative_regulation (inhibition) of p44
1) Confidence 0.41 Published 2000 Journal Glia Section Abstract Doc Link 10756074 Disease Relevance 0 Pain Relevance 0
This response was inhibited by the adenylyl cyclase, protein kinase A, mitogen-activated protein kinase (p42/p44), and epidermal growth factor receptor-specific tyrosine kinase inhibitors.
Negative_regulation (inhibitors) of p44
2) Confidence 0.18 Published 2006 Journal Pancreas Section Body Doc Link 16804413 Disease Relevance 0 Pain Relevance 0

General Comments

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