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Context Info
Confidence 0.28
First Reported 2000
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Prkaca) mitochondrion (Prkaca) Golgi apparatus (Prkaca)
protein complex (Prkaca) cytoplasm (Prkaca) cytosol (Prkaca)
Anatomy Link Frequency
pyramidal neurons 1
Vip (Rattus norvegicus)
Prkaca (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 8 100.00 Very High Very High Very High
Pyramidal cell 3 100.00 Very High Very High Very High
monoamine 1 98.40 Very High Very High Very High
Serotonin 1 95.28 Very High Very High Very High
Dopamine 1 93.20 High High
Neuropeptide 2 75.00 Quite High
tetrodotoxin 1 47.84 Quite Low


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We conclude that CRF, VIP, and CGRP suppress the slow Ca(2+)-activated K(+) current, I(sAHP), in CA1 hippocampal pyramidal neurons by activating the cAMP-dependent protein kinase, PKA.
VIP Positive_regulation (activating) of PKA in pyramidal neurons associated with pyramidal cell and calcitonin gene-related peptide
1) Confidence 0.28 Published 2000 Journal J. Neurophysiol. Section Abstract Doc Link 10758117 Disease Relevance 0 Pain Relevance 0.52

General Comments

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