INT877

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Context Info
Confidence 0.19
First Reported 1978
Last Reported 1983
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0
Pain Relevance 1.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Fdft1) endoplasmic reticulum (Fdft1) transferase activity, transferring alkyl or aryl (other than methyl) groups (Fdft1)
Anatomy Link Frequency
hypothalamus 4
Fdft1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Somatostatin 12 100.00 Very High Very High Very High
GABAergic 4 98.08 Very High Very High Very High
Action potential 2 87.52 High High
tetrodotoxin 4 81.16 Quite High
Serotonin 6 75.00 Quite High
gABA 6 74.48 Quite High
agonist 4 68.36 Quite High
anesthesia 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Regulation of somatostatin (SS) secretion was studied in an in vitro system using collagenase-dispersed cells from fetal rat hypothalamus maintained in long term monolayer culture.
Regulation (Regulation) of Localization (secretion) of SS in hypothalamus associated with somatostatin
1) Confidence 0.19 Published 1983 Journal Endocrinology Section Abstract Doc Link 6129132 Disease Relevance 0 Pain Relevance 0.43
GABAergic, cholinergic, and serotoninergic systems may thus interact at the level of the hypothalamus to modulate SS secretion in vivo and thereby influence anterior pituitary release of GH and TSH.
Regulation (modulate) of Localization (secretion) of SS in hypothalamus associated with gabaergic and somatostatin
2) Confidence 0.16 Published 1983 Journal Endocrinology Section Abstract Doc Link 6129132 Disease Relevance 0 Pain Relevance 0.68
On the other hand, pretreatment with anti-TRH did not affect the basal serum GH levels nor the anti-SS-induced GH release.
Neg (nor) Regulation (affect) of Localization (release) of anti-SS
3) Confidence 0.01 Published 1978 Journal Endocrinology Section Abstract Doc Link 107024 Disease Relevance 0 Pain Relevance 0.07

General Comments

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